Limitations in thrombolytic therapy in acute ischemic stroke

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dc.contributor.authorKocak, Sedat
dc.contributor.authorDogan, Emine
dc.contributor.authorKokcam, Melek
dc.contributor.authorGirisgin, Abdullah Sadik
dc.contributor.authorBodur, Said
dc.date.accessioned2024-02-23T14:45:36Z
dc.date.available2024-02-23T14:45:36Z
dc.date.issued2012
dc.departmentNEÜen_US
dc.description.abstractObjective: The eligibility for thrombolytic therapy for patients who present to the emergency department with Acute Ischaemic Stroke (AIS) has been researched in this study. Methodology: Patients who had presented to the emergency department of our hospital between March 2008-2009 and diagnosed as AIS clinically and radiologically were included in the study prospectively. Results: One hundred and twelve patients were included in the study. Forty nine (43.8 %) were female and the mean age was 68.7 +/- 12.2 (median 71.5). The mean time from the onset of symptom to hospital admission was 12.2 +/- 12.9 hours (median 6 hours). Two (1.8%) patients did not have any contraindication for thrombolytic therapy. Arrival time at the hospital of three hours and higher was the single contraindication in 40 (35.7%) patients. The most common four contraindications were delayed admission, multilobar infarct or hypodensity of more than 1/3 of the hemisphere, hypertension and mild neurological symptoms respectively. Conclusions: Our data suggest that the primary barrier to the delivery of thrombolytic therapy for AIS is delayed arrival of the patient to a hospital, and up to 1/3 of our patients, the percentage arriving within 4 hours of the onset of stroke symptoms, might be eligible for attempted re-perfusion.en_US
dc.identifier.endpage590en_US
dc.identifier.issn1682-024X
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84865164930en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage586en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17525
dc.identifier.volume28en_US
dc.identifier.wosWOS:000308383400004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherProfessional Medical Publicationsen_US
dc.relation.ispartofPakistan Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStrokeen_US
dc.subjectAcuteen_US
dc.subjectThrombolytic Therapyen_US
dc.titleLimitations in thrombolytic therapy in acute ischemic strokeen_US
dc.typeArticleen_US

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