Clinical and Laboratory Characteristics of COVID-19 Cases Followed in Selcuk University Faculty of Medicine

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dc.contributor.authorSumer, Sua
dc.contributor.authorUral, Onur
dc.contributor.authorAktug-Demir, Nazlim
dc.contributor.authorCifci, Seyma
dc.contributor.authorTurkseven, Burcu
dc.contributor.authorKilincer, Abidin
dc.contributor.authorTurk-Dagi, Hatice
dc.date.accessioned2024-02-23T14:41:11Z
dc.date.available2024-02-23T14:41:11Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractObjective: Understanding the natural course of COVID-19 and determining its clinical findings are essential for early diagnosis and treatment. In this study, we aimed to investigate clinical and laboratory characteristics of cases followed with a diagnosis of COVID-19 in Selcuk University Faculty of Medicine Department of Infectious Diseases and Clinical Microbiology. Methods: Among patients followed with a diagnosis of possible/definitive COVID-19, those with a positive SARS-CoV-2 RT-PCR test were evaluated retrospectively in terms of their clinical, laboratory and thorax computed tomography (CT) data. Results: Among 407 patients followed with a diagnosis of possible/definitive COVID-19, 149 (36.6%) were SARS-CoV-2 RT-PCR test-positive. 82 (55%) of the patients were female and 67 (45%) were male. Mean age was 49.3 +/- 7.6 years. 11 (7.4%) were health care workers. While the most common symptom was cough with 46.3%, fever was observed in 29.5%, sore throat in 27.5% and malaise in 26.8% of the patients. 94 (63.1%) of the patients had underlying diseases. Hypertension and diabetes mellitus were the most common underlying disease. Laboratory findings were leukopenia in 12 (8.1%), lymphopenia in 34 (22.8%), thrombocytopenia in 24 (16.1%), elevated D-dimer levels in 43 (28.9%), elevated lactate dehydrogenase levels in 73 (49%), and elevated C-reactive protein (CRP) levels in 45 (30.2%) patients. While 71 (47.6%) of the patients had normal thorax CT, 43 (28.9%) had mild pneumonia, and 35 (23.5%) moderate pneumonia. D-dimer and CRP levels were higher in those with pneumonia than those without pneumonia (p=0.001 and p=0.001, respectively). As the pneumonia level increased, the increase of D-dimer and CRP levels became evident (p=0.003 and p=0.001, respectively). Conclusions: The clinical course of COVID-19 patients varies. It is noteworthy that there is a positive correlation between the severity of pneumonia and the increase in D-dimer and CRP levels in COVID-19.en_US
dc.identifier.doi10.5152/kd.2020.26
dc.identifier.endpage127en_US
dc.identifier.issn1301-143X
dc.identifier.issn1309-1484
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85090537859en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage122en_US
dc.identifier.urihttps://doi.org/10.5152/kd.2020.26
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16747
dc.identifier.volume33en_US
dc.identifier.wosWOS:000569378600003en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherDoc Design Informatics Co Ltden_US
dc.relation.ispartofKlimik Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCovid-19en_US
dc.subjectSars-Cov-2en_US
dc.subjectPandemicsen_US
dc.subjectClinical Findingsen_US
dc.subjectDiagnosisen_US
dc.titleClinical and Laboratory Characteristics of COVID-19 Cases Followed in Selcuk University Faculty of Medicineen_US
dc.typeArticleen_US

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