Effects of Sevoflurane and Propofol Anesthesia on Cerebral Oxygenation in Patients Undergoing Carotid Endarterectomy

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dc.contributor.authorCura, Zeynep
dc.contributor.authorOc, Bahar
dc.contributor.authorArun, Oguzhan
dc.contributor.authorOc, Mehmet
dc.contributor.authorDuman, Ipek
dc.contributor.authorDuman, Ates
dc.date.accessioned2024-02-23T14:41:01Z
dc.date.available2024-02-23T14:41:01Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractAIM: To compare the effects of sevoflurane and propofol anesthesia on perioperative cerebral oxygenation in patients undergoing carotid endarterectomy (CEA) under general anesthesia by using near-infrared spectroscopy (NIRS) monitoring. MATERIAL and METHODS: Institutional approval was obtained, and the perioperative data of 33 patients undergoing CEA were retrospectively evaluated. The study groups were organized according to the anesthesia drugs used for maintenance: sevoflurane (n=17) and propofol (n=16). The regional cerebral oxygen saturation (rScO(2)) of the ipsilateral and contralateral hemispheres was monitored continuously using a NIRS instrument and analyzed at specific time points starting from induction to the 12th hour postoperation. The data were analyzed using the appropriate tests, and a p value of <0.05 was considered significant. RESULTS: Compared with those of groups with non-clamped hemispheres, the rScO(2) values of the sevoflurane and propofol groups decreased significantly during clamping (p<0.05) and increased to above-preoperative values after declamping (p<0.05). When the sevoflurane and propofol groups were compared, a significant decrease in rScO(2) was noted during extubation in the sevoflurane group (p<0.05). In the propofol group, female patients had significantly lower rScO(2) values compared with male patients during clamping of the carotid artery (p<0.05). None of the observed decreases was greater than 20%, which is considered an indication for shunting. CONCLUSION: Our NIRS monitoring results indicate that sevoflurane or propofol anesthesia does not generally cause significant differences in cerebral oxygenation during and after cross-clamping in patients undergoing CEA. The finding of sex-related differences in cerebral oxygenation in patients receiving propofol and decreased oxygenation during extubation in patients receiving sevoflurane warrants further studies.en_US
dc.identifier.doi10.5137/1019-5149.JTN.33776-21.2
dc.identifier.endpage82en_US
dc.identifier.issn1019-5149
dc.identifier.issue1en_US
dc.identifier.pmid34664695en_US
dc.identifier.scopus2-s2.0-85123264444en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage76en_US
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.33776-21.2
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16662
dc.identifier.volume32en_US
dc.identifier.wosWOS:000745906800001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Neurosurgical Socen_US
dc.relation.ispartofTurkish Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCarotid Endarterectomyen_US
dc.subjectCerebral Oxygenationen_US
dc.subjectNear-Infrared Spectroscopyen_US
dc.subjectPropofolen_US
dc.subjectSevofluraneen_US
dc.titleEffects of Sevoflurane and Propofol Anesthesia on Cerebral Oxygenation in Patients Undergoing Carotid Endarterectomyen_US
dc.typeArticleen_US

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