Quality of life, family burden and associated factors in relatives with obsessive-compulsive disorder

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dc.contributor.authorCicek, Erdinc
dc.contributor.authorCicek, Ismet Esra
dc.contributor.authorKayhan, Fatih
dc.contributor.authorUguz, Faruk
dc.contributor.authorKaya, Nazmiye
dc.date.accessioned2024-02-23T14:02:59Z
dc.date.available2024-02-23T14:02:59Z
dc.date.issued2013
dc.departmentNEÜen_US
dc.description.abstractObjective: The aim of this study is to assess the quality of life (QoL), family burden and psychiatric disorders in first-degree relatives of patients with obsessive-compulsive disorder (OCD) and to compare them with healthy controls and their relatives. Methods: Forty patients with OCD and 47 of their first-degree relatives as well as 40 healthy subjects and 45 of their first-degree relatives were recruited in this study. OCD and comorbid anxiety or mood disorders were determined by means of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders. Comorbid Axis II disorders were diagnosed with the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition Personality Disorders. Type and severity of obsessive-compulsive symptoms were assessed with the Yale-Brown Obsessive-Compulsive Scale, and the disability of patients with OCD was evaluated with the WHO DAS II. Family burden and QoL in the relatives were evaluated with the Zarit Burden Interview (ZBI) protocol and the World Health Organization Quality of Life Assessment-Brief, respectively. Results: The mean ZBI score of family members of OCD patients was higher than the control relatives. Linear regression analysis indicated that the independent factors associated with ZBI were duration of OCD, comorbid major depressive disorder and poorer insight. Compared with those of control relatives, the QoL of relatives of patients with OCD was significantly lower in all domains. While the diagnosis of major depressive disorder in relatives of OCD patients was significantly higher than the control relatives, the diagnosis of any anxiety disorder did not differ. Conclusions: Our study provides evidence that OCD not only affects the lives of patients but also their family members. (C) 2013 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.genhosppsych.2013.01.004
dc.identifier.endpage258en_US
dc.identifier.issn0163-8343
dc.identifier.issn1873-7714
dc.identifier.issue3en_US
dc.identifier.pmid23453525en_US
dc.identifier.scopus2-s2.0-84876956517en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage253en_US
dc.identifier.urihttps://doi.org/10.1016/j.genhosppsych.2013.01.004
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11928
dc.identifier.volume35en_US
dc.identifier.wosWOS:000318995800007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofGeneral Hospital Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObsessive-Compulsive Disorderen_US
dc.subjectFamilyen_US
dc.subjectBurdenen_US
dc.subjectQuality Of Lifeen_US
dc.titleQuality of life, family burden and associated factors in relatives with obsessive-compulsive disorderen_US
dc.typeArticleen_US

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