Severe ovarian hyperstimulation syndrome and gonadotropin-releasing hormone agonist trigger in patients with hypogonadotropic hypogonadism: A report of two cases

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dc.contributor.authorGurbuz, Ali Sami
dc.contributor.authorGode, Funda
dc.contributor.authorKilic, Fatma
dc.contributor.authorGurbuz, Zeynep Umay
dc.contributor.authorDeveer, Ruya
dc.date.accessioned2024-02-23T14:38:20Z
dc.date.available2024-02-23T14:38:20Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractOvarian Hyperstimulation syndrome (OHSS) is a rare condition in patients with hypogonadotropic hypogonadism. Two patients with hypogonadotropic hypogonadism are reported, a rare case of severe OHSS and a case of prevented OHSS via gonadotropin-releasing hormone (GnRH) agonist trigger, respectively. The first case was a 31-year-old patient. in vitro fertilization (IVF) treatment was performed three times but the patient never developed OHSS. The first patient was diagnosed as having severe OHSS on the ninth day after the fresh embryo transfer. She stayed 66 days in hospital and 50.5 litres of fluid were aspirated from her abdomen. The second case was a 26-year-old and primary infertile patient. She had never undergone IVF treatment. The GnRH agonist stimulation test was performed before IVF treatment. After the ovarian stimulation, GnRH agonist trigger was given. Thirty-two oocytes were retrieved from the ovaries and OHSS did not occur. Although severe OHSS is rare, it can develop in patients hypogonadotropic hypogonadism. If a GnRH stimulation test is performed before ovarian stimulation, OHSS can be prevented because the test allows agonist triggering instead of hCG in hypogonadotropic hypogonadism.en_US
dc.identifier.doi10.4274/tjod.galenos.2020.65031
dc.identifier.endpage317en_US
dc.identifier.issn2149-9322
dc.identifier.issn2149-9330
dc.identifier.issue4en_US
dc.identifier.pmid33343979en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage314en_US
dc.identifier.urihttps://doi.org/10.4274/tjod.galenos.2020.65031
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16467
dc.identifier.volume17en_US
dc.identifier.wosWOS:000598157300012en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurkish Journal Of Obstetrics And Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectArten_US
dc.subjectFreeze-Allen_US
dc.subjectGnrh Agonist Triggeren_US
dc.subjectHypogonadotropic Hypogonadismen_US
dc.subjectOhssen_US
dc.titleSevere ovarian hyperstimulation syndrome and gonadotropin-releasing hormone agonist trigger in patients with hypogonadotropic hypogonadism: A report of two casesen_US
dc.typeArticleen_US

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