ECTOPIC TSH-SECRETING PITUITARY ADENOMA IN NASOPHARYNGEAL REGION

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dc.contributor.authorAltay, F. P.
dc.contributor.authorKulaksizoglu, M.
dc.contributor.authorFenkci, S. M.
dc.contributor.authorYalcin, N.
dc.contributor.authorSagtas, E.
dc.date.accessioned2024-02-23T14:38:01Z
dc.date.available2024-02-23T14:38:01Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractObjective. TSH-secreting pituitary adenomas (TSH-omas) are very rare disorders. This report describes the diagnosis and treatment of a thyroid-stimulating hormone-secreting ectopic pituitary adenoma in the nasopharyngeal region. Subjects and Methods. We report a 37-year-old male patient with thyroid-stimulating hormone-secreting ectopic pituitary adenoma in nasopharyngeal region. Results. A patient suffering from sweating, palpitations, dizziness and abnormality in thyroid tests was referred to our clinic. Thyroid function tests showed high basal levels of free thyroxine (FT4), free tri-iodothyronine (FT3), and serum TSH. TRH stimulation test results indicated blunted response. Scintigraphy showed increased radionuclide uptake (iodine-123), and a thyroid ultrasound scan revealed diffuse enlargement of the thyroid gland. A pituitary MRI indicated a normal pituitary. However, MRI showed a mass in the nasopharynx that was confirmed with endoscopy. Endoscopic total endonasal resection was done and the mass was removed. The pathology reported a TSH-secreting pituitary adenoma. Conclusion. In this report, an identified case of thyroid-stimulating hormone-secreting ectopic pituitary adenoma in nasopharyngeal region is reported and it is the only tenth case in the literature indicated in the nasopharyngeal region. Ectopic TSH-omas should be considered during inappropriate secretion of TSH as a candidate cause to enable correct diagnosis and improve the treatment of patients.en_US
dc.identifier.doi10.4183/aeb.2021.521
dc.identifier.endpage527en_US
dc.identifier.issn1841-0987
dc.identifier.issn1843-066X
dc.identifier.issue4en_US
dc.identifier.pmid35747874en_US
dc.identifier.scopus2-s2.0-85132901019en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage521en_US
dc.identifier.urihttps://doi.org/10.4183/aeb.2021.521
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16335
dc.identifier.volume17en_US
dc.identifier.wosWOS:000810534800015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEditura Acad Romaneen_US
dc.relation.ispartofActa Endocrinologica-Bucharesten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTsh-Omaen_US
dc.subjectNasopharyngeal Regionen_US
dc.subjectEctopic Pituitary Adenomaen_US
dc.titleECTOPIC TSH-SECRETING PITUITARY ADENOMA IN NASOPHARYNGEAL REGIONen_US
dc.typeArticleen_US

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