Prevention of Propofol Injection Pain in Children: A Comparison of Pretreatment with Tramadol and Propofol-Lidocaine Mixture

Basit Öğe Kaydı
dc.contributor.authorBorazan, Hale
dc.contributor.authorSahin, Osman
dc.contributor.authorKececioglu, Ahmet
dc.contributor.authorUluer, M. Selcuk
dc.contributor.authorEt, Tayfun
dc.contributor.authorOtelcioglu, Seref
dc.date.accessioned2024-02-23T14:44:49Z
dc.date.available2024-02-23T14:44:49Z
dc.date.issued2012
dc.departmentNEÜen_US
dc.description.abstractBackground: The pain on propofol injection is considered to be a common and difficult to eliminate problem in children. In this study, we aimed to compare the efficacy of pretreatment with tramadol 1 mg.kg(-1) and propofol-lidocaine 20 mg mixture for prevention of propofol induced pain in children. Methods: One hundred and twenty ASA I-II patients undergoing orthopedic and otolaryngological surgery were included in this study and were divided into three groups with random table numbers. Group C (n=39) received normal saline placebo and Group T (n=40) received 1 mg. kg(-1) tramadol 60 sec before propofol (180 mg 1% propofol with 2 ml normal saline) whereas Group L (n=40) received normal saline placebo before propofol-lidocaine mixture (180 mg 1% propofol with 2 ml % 1 lidocaine). One patient in Group C was dropped out from the study because of difficulty in inserting an iv cannula. Thus, one hundred and nineteen patients were analyzed for the study. After given the calculated dose of propofol, a blinded observer assessed the pain with a four-point behavioral scale. Results: There were no significant differences in patient characteristics and intraoperative variables (p>0.05) except intraoperative fentanyl consumption and analgesic requirement one hr after surgery among the groups (p<0.05). Both tramadol 1 mg. kg-1 and lidocaine 20 mg mixture significantly reduced propofol pain when compared with control group. Moderate and severe pain were found higher in control group (p<0.05). The incidence of overall pain was 79.4% in the control group, 35% in tramadol group, 25% in lidocaine group respectively (p<0.001). Conclusions: Pretreatment with tramadol 60 sec before propofol injection and propofol-lidocaine mixture were significantly reduced propofol injection pain when compared to placebo in children.en_US
dc.identifier.doi10.7150/ijms.4793
dc.identifier.endpage497en_US
dc.identifier.issn1449-1907
dc.identifier.issue6en_US
dc.identifier.pmid22927775en_US
dc.identifier.scopus2-s2.0-84866023382en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage492en_US
dc.identifier.urihttps://doi.org/10.7150/ijms.4793
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17130
dc.identifier.volume9en_US
dc.identifier.wosWOS:000308126600013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIvyspring Int Publen_US
dc.relation.ispartofInternational Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTramadolen_US
dc.subjectLidocaineen_US
dc.subjectPropofolen_US
dc.subjectPainen_US
dc.subjectChildrenen_US
dc.titlePrevention of Propofol Injection Pain in Children: A Comparison of Pretreatment with Tramadol and Propofol-Lidocaine Mixtureen_US
dc.typeArticleen_US

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