Comparison of Parkinson?s patients with and without COVID-19 in terms of prognosis

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dc.contributor.authorEren, Fettah
dc.contributor.authorDikmen, Yagizhan
dc.contributor.authorGur, Merve Nur
dc.contributor.authorEkmekci, Ahmet Hakan
dc.contributor.authorSumer, Sua
dc.contributor.authorOzturk, Serefnur
dc.date.accessioned2024-02-23T14:41:32Z
dc.date.available2024-02-23T14:41:32Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractBackground & Objectives: This study aimed to compare PD patients with and without COVID-19 and to evaluate the associated factors about prognosis.Methods: The data of 37 hospitalized PD patients associated with COVID-19 pneumonia were evaluated. It was compared with the data of 40 PD patients who did not have COVID-19 in the same period. Clinical findings, prognosis, mortality and other related factors were compared in PD patients with and without COVID-19.Results: Hypertension was higher comorbid disease in PD patients with COVID-19 (p = 0.005). The duration of PD was longer in patients without COVID-19 disease (6.02 +/- 2.80 vs 5.08 +/- 4.59) (p = 0.028). In PD patients with COVID-19, the most common symptoms were myalgia-arthralgia (73.0%) and fatigue (48.6%). Intensive care was required in 17 (45.9%) patients, and invasive mechanical ventilation (IMV) was required in 9 (24.3%) patients. The in-hospital mortality rate was 29.7% (n = 11). Mortality and IMV requirement were higher in patients whose initial symptom was diarrhea (p = 0.004, p = 0.008, respectively). No correlation was detected between PD stage, treatment options and prognosis (p < 0.05).Conclusion: Mortality rate and IMV requirement are higher in PD patients with COVID-19 pneumonia, particularly in patients with initial symptoms of diarrhea. These patients should be followed more carefully in terms of probable poor prognosis.en_US
dc.identifier.doi10.54029/2023dfx
dc.identifier.endpage177en_US
dc.identifier.issn1823-6138
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85153507766en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage169en_US
dc.identifier.urihttps://doi.org/10.54029/2023dfx
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16884
dc.identifier.volume28en_US
dc.identifier.wosWOS:000960957000019en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAsean Neurological Assocen_US
dc.relation.ispartofNeurology Asiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectParkinson?S Diseaseen_US
dc.subjectCovid-19en_US
dc.subjectIntensive Careen_US
dc.subjectMortalityen_US
dc.subjectMechanical Ventilationen_US
dc.titleComparison of Parkinson?s patients with and without COVID-19 in terms of prognosisen_US
dc.typeArticleen_US

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