Prolonged P-Wave and QT Dispersion in Children with Inflammatory Bowel Disease in Remission

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dc.contributor.authorBornaun, Helen Aghdasi
dc.contributor.authorYilmaz, Nuh
dc.contributor.authorKutluk, Gunsel
dc.contributor.authorDedeoglu, Reyhan
dc.contributor.authorOztarhan, Kazim
dc.contributor.authorKeskindemirci, Gonca
dc.contributor.authorTulunoglu, Aras
dc.date.accessioned2024-02-23T14:26:31Z
dc.date.available2024-02-23T14:26:31Z
dc.date.issued2017
dc.departmentNEÜen_US
dc.description.abstractObjectives. Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases (IBD) with unclear underlying aetiologies. Severe cardiac arrhythmias have been emphasised in a few studies on adult IBD patients. This study aimed to investigate the alteration of the P-wave and QT interval dispersion parameters to assess the risk of atrial conduction and ventricular repolarisation abnormalities in pediatric IBD patients. Patients and Methods. Thirty-six IBD patients in remission (UC: 20, CD: 16) aged 3-18 years and 36 age- and sex-matched control patients were enrolled in the study. Twelve-lead electrocardiograms were used to determine durations of P-wave, QT, and corrected QT (QTc) interval dispersion. Transthoracic echocardiograms and 24-hour rhythm Holter recordings were obtained for both groups. Results. The P-wave dispersion, QT dispersion, and QTc interval dispersion (Pdisp, QTdisp, and QTcdisp) were significantly longer in the patient group. The mean values of Pminimum, Pmaximum, and QTcminimum were significantly different between the two groups. The echocardiography and Holter monitoring results were not significantly different between the groups. Furthermore, no differences in these parameters were detected between the CD and UC groups. Conclusion. Results suggest that paediatric IBD patients may carry potential risks for serious atrial and ventricular arrhythmias over time even during remission.en_US
dc.identifier.doi10.1155/2017/6960810
dc.identifier.issn2314-6133
dc.identifier.issn2314-6141
dc.identifier.pmid28316985en_US
dc.identifier.scopus2-s2.0-85017548466en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1155/2017/6960810
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14233
dc.identifier.volume2017en_US
dc.identifier.wosWOS:000396223700001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofBiomed Research Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleProlonged P-Wave and QT Dispersion in Children with Inflammatory Bowel Disease in Remissionen_US
dc.typeArticleen_US

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