Factors predicting postoperative febrile urinary tract infection following percutaneous nephrolithotomy in prepubertal children

Basit Öğe Kaydı
dc.contributor.authorKaygisiz, Onur
dc.contributor.authorSatar, Nihat
dc.contributor.authorGunes, Ali
dc.contributor.authorDogan, Hasan Serkan
dc.contributor.authorErozenci, Ahmet
dc.contributor.authorOzden, Ender
dc.contributor.authorPiskin, Mehmet Mesut
dc.date.accessioned2024-02-23T14:13:03Z
dc.date.available2024-02-23T14:13:03Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractBackground Predictive tables and scoring systems can predict stone clearance. However, there is a paucity of evidence regarding the prediction of complications during percutaneous nephrolithotomy (PCNL), particularly in children, which remains under-researched. To our knowledge, no studies have evaluated the risk factors for febrile urinary tract infection (FUTI) after pediatric PCNL. Objectives To assess the predictive factors of FUTI in prepubertal children after PCNL and determine whether any prophylactic cephalosporins are superior for decreasing the FUTI rate. Study design Data from 1157 children who underwent PCNL between 1991 and 2012 were retrieved from the multicenter database of the Turkish Pediatric Urology Society. Children >12 years of age were excluded, leaving 830 children (364 girls, 466 boys). Data were analyzed according to the presence of FUTI and compared between the FUTI and non-FUTI groups. Results Mean age was 6.46 +/- 3.38 years. Twenty-nine (3.5%) children had FUTI which was confirmed by urine culture. FUTI Table Predictive factors for FUTI. occurred more frequently in young children (5.5%) than school-age children (2.4%). In univariate analysis, there were significant differences between the FUTI and non-FUTI groups regarding age, cephalosporin subgroup (first, second and third generation cephalosporin), side of PCNL, staghorn stones, tract size, operative time, postoperative ureteral catheter usage, perioperative complications (SATAVA), and blood transfusion. Multivariate analysis revealed that age, side of PCNL, staghorn stones, tract size, operative time, and blood transfusion were independent predictors of FUTI. Discussion The smaller tract size could cause FUTI with poor fluid drainage that may lead to elevate renal pelvic pressure and trigger bacteremia-causing pyelovenous backflow. Filling the calyx and renal pelvis by a staghorn stone and the resulting obstruction of fluid drainage may elevate intrarenal pelvis pressure. Longer operative time is likely to increase renal pelvic pressure over longer periods, which may account for FUTI after pediatric PCNL. Conclusions Younger age, right-sided PCNL, staghorn stones, mini-PCNL, longer operative time, and blood transfusion are risk factors for FUTI. First-, second-, and third-generation cephalosporins are equally effective for prophylaxis in prepubertal children undergoing PCNL.en_US
dc.description.sponsorshipScientific Research Projects Coordination Unit of Istanbul University [1030-24135]en_US
dc.description.sponsorshipBulent Onal was supported by Scientific Research Projects Coordination Unit of Istanbul University. Project number 1030-24135.en_US
dc.identifier.doi10.1016/j.jpurol.2018.04.010
dc.identifier.endpage+en_US
dc.identifier.issn1477-5131
dc.identifier.issn1873-4898
dc.identifier.issue5en_US
dc.identifier.pmid29779995en_US
dc.identifier.scopus2-s2.0-85047083181en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage448en_US
dc.identifier.urihttps://doi.org/10.1016/j.jpurol.2018.04.010
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12272
dc.identifier.volume14en_US
dc.identifier.wosWOS:000451374800039en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofJournal Of Pediatric Urologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChilden_US
dc.subjectFeveren_US
dc.subjectKidney Calculien_US
dc.subjectNephrostomyen_US
dc.subjectPercutaneousen_US
dc.subjectUrinary Tract Infectionsen_US
dc.titleFactors predicting postoperative febrile urinary tract infection following percutaneous nephrolithotomy in prepubertal childrenen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu