Minimal Clinically Important Difference of Carpal Tunnel Release in Diabetic and Nondiabetic Patients

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dc.contributor.authorOzer, Kagan
dc.contributor.authorMalay, Sunitha
dc.contributor.authorToker, Serdar
dc.contributor.authorChung, Kevin C.
dc.date.accessioned2024-02-23T14:21:18Z
dc.date.available2024-02-23T14:21:18Z
dc.date.issued2013
dc.departmentNEÜen_US
dc.description.abstractBackground: Establishing the minimal clinically important difference for patient-reported outcomes questionnaires is essential in outcomes research to evaluate the patient's perspective of treatment effectiveness. The authors aim to determine the minimal clinically important difference after carpal tunnel release in diabetic and nondiabetic patients using the Boston Carpal Tunnel Questionnaire. Methods: The authors prospectively evaluated 114 patients (87 nondiabetic and 27 diabetic patients) undergoing carpal tunnel release. In addition to standard history and physical examination, the authors obtained preoperative electrodiagnostic studies to confirm carpal tunnel syndrome. The Boston Carpal Tunnel Questionnaire was administered before and after surgery at 3 and 6 months. Patients were asked about their level of satisfaction at the final follow-up visit. The authors applied the receiver operating characteristic curve approach to determine the minimal clinically important difference of symptom and function severity scales of the questionnaire. The authors used patient satisfaction as the reference standard to compare against the standardized change in scores after surgery for the two groups. Results: For both diabetic and nondiabetic patients, symptom and function severity scales showed large effect sizes of greater than 0.8 at 3 and 6 months after surgery. At 6 months after surgery, to be satisfied, diabetic patients required a minimal clinically important difference of 1.55 and 2.05 for symptom and function scales, respectively, whereas nondiabetic patients required 1.45 and 1.6, respectively. Conclusions: Diabetic patients needed a greater improvement in Boston Carpal Tunnel Questionnaire score to be satisfied on functional and symptom severity scales than nondiabetic patients. Overall, diabetic patients had less improvement in Boston Carpal Tunnel Questionnaire final scores compared with nondiabetics.en_US
dc.description.sponsorshipNational Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health [K24 AR053120]en_US
dc.description.sponsorshipResearch reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award K24 AR053120 (to K.C.C.).en_US
dc.identifier.doi10.1097/PRS.0b013e31828bd6ec
dc.identifier.endpage1285en_US
dc.identifier.issn0032-1052
dc.identifier.issn1529-4242
dc.identifier.issue6en_US
dc.identifier.pmid23416439en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1279en_US
dc.identifier.urihttps://doi.org/10.1097/PRS.0b013e31828bd6ec
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13540
dc.identifier.volume131en_US
dc.identifier.wosWOS:000319567500042en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofPlastic And Reconstructive Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleMinimal Clinically Important Difference of Carpal Tunnel Release in Diabetic and Nondiabetic Patientsen_US
dc.typeArticleen_US

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