Histopathological evaluation of the effect of hyperbaric oxygen therapy on capsule occurrence around silicone breast prosthesis: an experimental study

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dc.contributor.authorYarar, Serhat
dc.contributor.authorArslan, Abdullah
dc.contributor.authorInce, Bilsev
dc.contributor.authorYildirim, Mehmet Emin Cem
dc.contributor.authorOltulu, Pembe
dc.contributor.authorUyar, Ilker
dc.contributor.authorDadaci, Mehmet
dc.date.accessioned2024-02-23T14:20:44Z
dc.date.available2024-02-23T14:20:44Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractBackground In general, capsular contracture is the underlying cause of complications such as pain, stiffening, breast asymmetry, and animation deformity that are seen in the late postoperative period due to the use of silicone breast prostheses. Considering the positive effects of HBO therapy on wound healing, the objective of this study was to investigate the effect of HBO therapy on capsule reaction occurring due to silicone implants. Material and Methods Rats were divided into four groups. 1 cm x 1 cm silicone implants with rough surface were inserted in subcutaneous plane on the m spinotrapezius muscle fascia at just right of the dorsal region midline in rats in Group 1, while implants with same properties were inserted beneath m spinotrapezius muscle in rats in Group 2. Implants with the same properties were inserted in the subcutaneous area on the m spinotrapezius muscle in rats in Group 3 and into the area under the muscle in rats in Group 4. Beginning from the first postoperative day, rats in Groups 3 and 4 received HBO therapy for 90 min under 2.5 ATM pressure as one session a day over 15 days. Results The mean capsule thickness was statistically significantly lower in the groups treated with HBO compared to the control groups. Fibroblast, neutrophil and macrophage counts were statistically significantly lower in the groups treated with HBO compared to the control groups. Conclusion We believe that HBO therapy can be used as an adjuvant treatment options to decrease capsule contraction occurring after silicone implant application.en_US
dc.identifier.doi10.1080/2000656X.2020.1838296
dc.identifier.endpage122en_US
dc.identifier.issn2000-656X
dc.identifier.issn2000-6764
dc.identifier.issue2en_US
dc.identifier.pmid33176522en_US
dc.identifier.scopus2-s2.0-85096102620en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage118en_US
dc.identifier.urihttps://doi.org/10.1080/2000656X.2020.1838296
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13275
dc.identifier.volume55en_US
dc.identifier.wosWOS:000588541300001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Plastic Surgery And Hand Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectImplantsen_US
dc.subjectPlastic Surgeryen_US
dc.titleHistopathological evaluation of the effect of hyperbaric oxygen therapy on capsule occurrence around silicone breast prosthesis: an experimental studyen_US
dc.typeArticleen_US

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