Prognostic nutritional index and the risk of acute kidney injury in patients with acute coronary syndrome

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dc.contributor.authorSertdemir, Ahmet Lutfu
dc.contributor.authorIcli, Abdullah
dc.contributor.authorAribas, Alpay
dc.contributor.authorTatar, Sefa
dc.contributor.authorAkilli, Nazire Belgin
dc.contributor.authorAlsancak, Yakup
dc.contributor.authorAkilli, Hakan
dc.date.accessioned2024-02-23T14:30:09Z
dc.date.available2024-02-23T14:30:09Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractOBJECTIVE: Recent studies have linked malnutrition with undesirable outcomes in cardiovascular diseases. However, the underlying mechanism is unknown. Contrast-induced acute kidney injury (CI-AKI) increased cardiovascular mortality after percutaneous coronary intervention (PCI). This study hypothesizes that prognostic nutritional index (PNI) plays a role in the development of CI-AKI in patients with acute coronary syndrome undergoing emergency PCI. METHODS: This study enrolled 551 patients. PNI was determined as 10x serum albumin (g/dL)+0.005xtotal lymphocyte count (mm(3)). CI-AKI was characterized as the increase in serum creatinine >= 0.3 mg/dL level within 48 h after PCI. Patients were classified as either CI-AKI (+) or CI-AKI (-). RESULTS: CI-AKI has occurred in 72 of 551 patients (13.1%). PNI was significantly lower in the CI-AKI (+) group than in the CI-AKI (-) group (44.4 +/- 6.6 versus 47.2 +/- 5.8, p<0.001, respectively). Multivariate logistic regression analysis showed that PNI [odds ratio, OR: 1.631, 95% confidence interval (CI): 1.168-2.308, p=0.02] and estimated glomerular filtration rate (OR: 3.26, 95%CI 1.733-6.143, p<0.001) were independent risk factors for CI-AKI. CONCLUSIONS: PNI is an independent risk factor for CI-AKI. The development of CI-AKI may be the mechanism responsible for the relationship between poor nutritional status and adverse cardiac events.en_US
dc.identifier.doi10.1590/1806-9282.20210460
dc.identifier.endpage1129en_US
dc.identifier.issn0104-4230
dc.identifier.issn1806-9282
dc.identifier.issue8en_US
dc.identifier.pmid34669857en_US
dc.identifier.scopus2-s2.0-85118304067en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1124en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.20210460
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15035
dc.identifier.volume67en_US
dc.identifier.wosWOS:000708990100012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPrognostic Nutritional Indexen_US
dc.subjectAcute Kidney Injuryen_US
dc.subjectAcute Coronary Syndromeen_US
dc.subjectPercutaneous Coronary Interventionen_US
dc.titlePrognostic nutritional index and the risk of acute kidney injury in patients with acute coronary syndromeen_US
dc.typeArticleen_US

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