Long-term metabolic cage housing increases anxiety/depression-related behaviours in adult male rats

Basit Öğe Kaydı
dc.contributor.authorSahin, Zafer
dc.contributor.authorSolak, Hatice
dc.contributor.authorKoc, Aynur
dc.contributor.authorKoca, Raviye Ozen
dc.contributor.authorOzkurkculer, Alpaslan
dc.contributor.authorCakan, Pinar
dc.contributor.authorGormus, Zulfikare Isik Solak
dc.date.accessioned2024-02-23T14:20:34Z
dc.date.available2024-02-23T14:20:34Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractThere are several reports on unfavourable effects of metabolic cage housing on animal welfare mainly due to the characteristic structures of these cages such as single housing and grid flooring. This study was aimed to compare the effects of long-term metabolic cage housing and conventional housing (normal grouped housing in standard cages) on the anxiety/depression-like behaviours in male rats. Anxiety/depression-related behaviours were evaluated by use of forced swimming test and open field test. Swimming and climbing were significantly lower and immobility duration higher in the metabolic cage group. In the open field test, total distance, mean velocity, time spent in the central area, zone transition, grooming, and rearing scores were significantly lower in the metabolic cage. Moreover, serum corticosterone level was higher in the metabolic cage group. The results of the study indicate that long-term metabolic cage housing may cause an increase in the anxiety- and depression-related behaviours in male rats.en_US
dc.identifier.doi10.1080/13813455.2018.1441314
dc.identifier.endpage127en_US
dc.identifier.issn1381-3455
dc.identifier.issn1744-4160
dc.identifier.issue2en_US
dc.identifier.pmid29463132en_US
dc.identifier.scopus2-s2.0-85042237165en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage122en_US
dc.identifier.urihttps://doi.org/10.1080/13813455.2018.1441314
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13217
dc.identifier.volume125en_US
dc.identifier.wosWOS:000462366900004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofArchives Of Physiology And Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMetabolic Cageen_US
dc.subjectCorticosteroneen_US
dc.subjectStressen_US
dc.subjectAnxietyen_US
dc.subjectDepressionen_US
dc.titleLong-term metabolic cage housing increases anxiety/depression-related behaviours in adult male ratsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu