Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes

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dc.contributor.authorOnk, Didem
dc.contributor.authorAyazoglu, Tulin Akarsu
dc.contributor.authorOnk, Oruc Alper
dc.contributor.authorAksut, Mehmet
dc.contributor.authorGunay, Murat
dc.contributor.authorTurkmen, Kultigin
dc.contributor.authorOzensoy, Aynur
dc.date.accessioned2024-02-23T14:26:31Z
dc.date.available2024-02-23T14:26:31Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractIntroduction. Increased levels of stress hormones are associated with mortality in patients undergoing coronary artery bypass grafting (CABG). Aim. To compare total intravenous anaesthesia (TIVA) and desflurane added to a subanaesthetic dose of propofol. Material and Methods. Fifty patients were enrolled in this study. Fentanyl (3-5mcg/kg/h) was started in both groups. Patients were divided into two groups. The PD group (n = 25) received 1 minimum alveolar concentration (MAC) desflurane anaesthesia in addition to propofol infusion (2-3 mg/kg/h), while P group (n = 25) received propofol infusion (5-6 mg/kg/h) only. Biochemical data, cortisol, and insulin levels were measured preoperatively (T0), after initiation of CPB but before cross-clamping the aorta (T1), after removal of the cross-clamp (T2), and at the 24th postoperative hour (T3). Results. Systolic, diastolic, and mean arterial pressure levels were significantly higher in PD group than those in P group in T1 and T2 measurements (p <= 0.05). CK-MB showed a significant decrease in group P (p <= 0.05). When we compared both groups, cortisol levels were significantly higher in PD group than P group (p <= 0.05). Conclusion. Stress and haemodynamic responses were better controlled using TIVA than desflurane inhalation added to a subanaesthetic dose of propofol in patients undergoing CABG.en_US
dc.identifier.doi10.1155/2016/3272530
dc.identifier.issn2314-6133
dc.identifier.issn2314-6141
dc.identifier.pmid27547757en_US
dc.identifier.scopus2-s2.0-85006150306en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1155/2016/3272530
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14230
dc.identifier.volume2016en_US
dc.identifier.wosWOS:000381150500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofBiomed Research Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleComparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changesen_US
dc.typeArticleen_US

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