Clinical and laboratory assessment for the inflammation role in chronic spontaneous urticaria: A clinical study

dc.contributor.authorAtaseven, Arzu
dc.contributor.authorDurmaz, Koray
dc.contributor.authorTemiz, Selami Aykut
dc.contributor.authorDursun, Recep
dc.date.accessioned2024-02-23T14:24:06Z
dc.date.available2024-02-23T14:24:06Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractChronic spontaneous urticaria (CSU) is triggered by unknown causes. We would like to explore the possible effect of hemogram parameters and several biochemical markers on CSU presence and also the severity of the disease. We also aimed to discuss the relationship between CSU and inflammation associated with these values. The study was planned prospectively. We selected patients already diagnosed with CSU who applied to the dermatology outpatient clinic and healthy controls. The patients and the healthy controls were tested for complete blood count, neutrophil/lymphocytes ratio and platelets/lymphocytes ratio, erythrocyte sedimentation rate, C-reactive protein, serum albumin and total bilirubin and indirect bilirubin levels. Urticaria activity score over 7 days (UAS-7) was calculated for the CSU patients. Forty patients with CSU and 55 healthy subjects were included in the study. Mean white blood cell (WBC) count is 8.37 +/- 2.14 in the patients' group and 7.41 +/- 2.01 in the healthy subjects group. Mean neutrophil (NEU) count is 4.88 +/- 1.65 in the patients' group and 4.19 +/- 1.39 in the healthy subjects group. Mean platelets (PLT) count is 308.48 +/- 88.32 in the patients' group and 268.65 +/- 64.80 in the healthy subjects group. We also detected positive correlations between UAS-7 score-WBC counts and UAS-7 score-NEU counts. Future studies are needed to investigate this possible relationship and confirm these results.en_US
dc.identifier.doi10.1111/dth.14125
dc.identifier.issn1396-0296
dc.identifier.issn1529-8019
dc.identifier.issue6en_US
dc.identifier.pmid32761761en_US
dc.identifier.scopus2-s2.0-85090134666en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1111/dth.14125
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13821
dc.identifier.volume33en_US
dc.identifier.wosWOS:000565688600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofDermatologic Therapyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlbuminen_US
dc.subjectBilirubinen_US
dc.subjectChronic Spontaneous Urticariaen_US
dc.subjectInflammationen_US
dc.titleClinical and laboratory assessment for the inflammation role in chronic spontaneous urticaria: A clinical studyen_US
dc.typeArticleen_US

Dosyalar