Lateral flow assays for detection of disease biomarkers

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dc.contributor.authorGumus, Eda
dc.contributor.authorBingol, Haluk
dc.contributor.authorZor, Erhan
dc.date.accessioned2024-02-23T14:13:01Z
dc.date.available2024-02-23T14:13:01Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractEarly diagnosis saves lives in many diseases. In this sense, monitoring of biomarkers is crucial for the diagnosis of diseases. Lateral flow assays (LFAs) have attracted great attention among paper-based point-of-care testing (POCT) due to their low cost, user-friendliness, and time-saving advantages. Developments in the field of health have led to an increase of interest in these rapid tests. LFAs are used in the diagnosis and monitoring of many diseases, thanks to biomarkers that can be observed in body fluids. This review covers the recent advances dealing with the design and strategies for the development of LFA for the detection of biomarkers used in clinical applications in the last 5 years. We focus on various strategies such as choosing the nanoparticle type, single or multiple test approaches, and equipment for signal transducing for the detection of the most common biomarkers in different diseases such as cancer, cardiovascular, infectious, and others including Parkinson's and Alzheimer's diseases. We expect that this study will contribute to the different approaches in LFA and pave the way for other clinical applications.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkiye (TUBITAK) [219Z054]en_US
dc.description.sponsorshipHB and EZ express their deep thanks to the Scientific and Technological Research Council of Turkiye (TUBITAK) for financial support (Grant number: 219Z054).en_US
dc.identifier.doi10.1016/j.jpba.2022.115206
dc.identifier.issn0731-7085
dc.identifier.issn1873-264X
dc.identifier.pmid36586382en_US
dc.identifier.scopus2-s2.0-85145314862en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.jpba.2022.115206
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12259
dc.identifier.volume225en_US
dc.identifier.wosWOS:000913449500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal Of Pharmaceutical And Biomedical Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLateral Flow Assayen_US
dc.subjectBiomarker Detectionen_US
dc.subjectPoint Of Careen_US
dc.subjectDiseaseen_US
dc.titleLateral flow assays for detection of disease biomarkersen_US
dc.typeArticleen_US

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