Association of Tourette syndrome and obsessive-compulsive disorder with allergic diseases in children and adolescents: a preliminary study

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dc.contributor.authorYuce, M.
dc.contributor.authorGuner, S. N.
dc.contributor.authorKarabekiroglu, K.
dc.contributor.authorBaykal, S.
dc.contributor.authorKilic, M.
dc.contributor.authorSancak, R.
dc.contributor.authorKarabekiroglu, A.
dc.date.accessioned2024-02-23T14:45:56Z
dc.date.available2024-02-23T14:45:56Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractOBJECTIVES: To investigate the rate of allergic diseases including asthma, allergic rhinitis and eczema in children and adolescents diagnosed with obsessive-compulsive disorder (OCD) (n:26) and/or Tourette syndrome (TS) (n:32) [OCD plus TS, n:13] compared to control subjects (n:35) [total, n:80]. PATIENTS AND METHODS: The symptoms of any allergic disease were assessed using the ISAAC questionnaire form. Allergy diagnoses were made by a pediatric allergy specialist. Skin prick tests were applied, and IgE levels and eosinophil counts were measured. RESULTS: While only one-fifth of the control subjects had allergic diseases, more than half of the children with TS and/or OCD had comorbid allergic diseases. Positive skin prick tests were greater in OCD patients compared to control subjects. There were no significant differences between the groups in terms of eosinophil counts or IgE levels. Among the allergic diseases, while allergic rhinitis was diagnosed at significantly higher rates in TS patients, eczema was significantly higher in OCD patients compared to control subjects. CONCLUSIONS: This preliminary study shows an association between allergic diseases and TS and/or OCD. The results revealing differences in associations between types of allergic disease (rhinitis or eczema) and neuropsychiatric disorder (tic disorder or OCD) need to be investigated in further studies with higher numbers of participants, and immune markers should be examined.en_US
dc.identifier.endpage310en_US
dc.identifier.issn1128-3602
dc.identifier.issue3en_US
dc.identifier.pmid24563428en_US
dc.identifier.scopus2-s2.0-84896909929en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage303en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17707
dc.identifier.volume18en_US
dc.identifier.wosWOS:000341967500002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical And Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChildrenen_US
dc.subjectTourette Syndromeen_US
dc.subjectObsessive-Compulsive Disorderen_US
dc.subjectAllergyen_US
dc.titleAssociation of Tourette syndrome and obsessive-compulsive disorder with allergic diseases in children and adolescents: a preliminary studyen_US
dc.typeArticleen_US

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