The effects of resveratrol administration on lipid oxidation in experimental renal ischemia-reperfusion injury in rats

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dc.contributor.authorBaltaci, A. K.
dc.contributor.authorGokbudak, H.
dc.contributor.authorBaltaci, S. B.
dc.contributor.authorMogulkoc, R.
dc.contributor.authorAvunduk, M. C.
dc.date.accessioned2024-02-23T14:20:28Z
dc.date.available2024-02-23T14:20:28Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractWe investigated how resveratrol affects lipid oxidation during experimental renal ischemia-reperfusion injury in rats. We used 48 adult male rats assigned to five groups: group 1, control; group 2, renal ischemia; group 3, renal ischemia + reperfusion; group 4, resveratrol + renal ischemia; group 5, resveratrol + renal ischemia + reperfusion. Plasma and renal tissue malondialdehyde (MDA), and erythrocyte and renal tissue glutathione (GSH) levels were measured and histologic changes in the renal tissue were examined. Ischemia-reperfusion affected the MDA-GSH balance adversely and caused histopathological changes in the renal tissue of the ischemia and ischemia + reperfusion groups. Resveratrol treatment normalized MDA and GSH levels as well as the histopathology that occurred in the renal tissue of the ischemia and ischemia + reperfusion groups.en_US
dc.description.sponsorshipScientific Research Projects Coordinatorship of Selcuk University [13202027]en_US
dc.description.sponsorshipThis work was supported by the Scientific Research Projects Coordinatorship of Selcuk University [SUBAPK; project no. 13202027].en_US
dc.identifier.doi10.1080/10520295.2019.1612091
dc.identifier.endpage599en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue8en_US
dc.identifier.pmid31271315en_US
dc.identifier.scopus2-s2.0-85068565705en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage592en_US
dc.identifier.urihttps://doi.org/10.1080/10520295.2019.1612091
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13163
dc.identifier.volume94en_US
dc.identifier.wosWOS:000474111500001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnic & Histochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHistopathologyen_US
dc.subjectLipid Oxidationen_US
dc.subjectRaten_US
dc.subjectRenal Ischemiaen_US
dc.subjectReperfusionen_US
dc.subjectResveratrolen_US
dc.titleThe effects of resveratrol administration on lipid oxidation in experimental renal ischemia-reperfusion injury in ratsen_US
dc.typeArticleen_US

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