Relationship of acanthosis nigricans with metabolic syndrome in obese children

Basit Öğe Kaydı
dc.contributor.authorDaye, Munise
dc.contributor.authorEklioglu, Beray Selver
dc.contributor.authorAtabek, Mehmet Emre
dc.date.accessioned2024-02-23T14:31:52Z
dc.date.available2024-02-23T14:31:52Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractObjectives: Acanthosis nigricans is a skin symptom in obesity that helps to identify patients at high risk for dyslipidemia, hypertension, insulin resistance, and diabetes. It is the most important complication of obesity in metabolic syndrome. Studies investigating the relationship between acanthosis nigricans and metabolic syndrome in obese children are insufficient. In our study, the relationship of acanthosis nigricans and metabolic syndrome was evaluated in children. Methods: Obese children aged between 6 and 18 years old, who were examined in the pediatric endocrinology outpatient clinic, were included. The patients' anthropometric measurements and laboratory results were recorded. Modified IDF (International Diabetes Federation) criteria for children were used in metabolic syndrome classification. Results: A hundred and forty-eight obese children were evaluated. The mean age of the cases was 11.91 +/- 2.94 years old. Of the cases, 56.1% were female (n=83) 43.9% (n=65) were male. In 39.9% (n=59) of cases, acanthosis nigricans was determined. Acanthosis nigricans was mostly located in the axillary area (27.1%) and the neck (16.9%). In 55.9% of the cases, it was located in more than one area. The relation of regionally detected acanthosis nigricans and metabolic syndrome was not significant (p=0.291). Metabolic syndrome was detected in 14% of 136 patients according to IDF criteria. Acanthosis nigricans and metabolic syndrome combination was present in 27.7%; however, 6.7% of the metabolic syndrome patients did not have acanthosis nigricans. There was a strong relation between metabolic syndrome and the presence of acanthosis nigricans (p=0.003). Conclusions: In our study, a correlation between acanthosis nigricans and metabolic syndrome was detected. Acanthosis nigricans is a skin sign that can be easily detected by clinician. It is an important and easy-to-detect dermatosis that helps determine patients at risk of metabolic syndrome in obese children.en_US
dc.identifier.doi10.1515/jpem-2020-0154
dc.identifier.endpage1568en_US
dc.identifier.issn0334-018X
dc.identifier.issn2191-0251
dc.identifier.issue12en_US
dc.identifier.pmid33581705en_US
dc.identifier.scopus2-s2.0-85096991006en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1563en_US
dc.identifier.urihttps://doi.org/10.1515/jpem-2020-0154
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15388
dc.identifier.volume33en_US
dc.identifier.wosWOS:000595142500007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofJournal Of Pediatric Endocrinology & Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcanthosis Nigricansen_US
dc.subjectChildrenen_US
dc.subjectHyperglycemiaen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectObesityen_US
dc.titleRelationship of acanthosis nigricans with metabolic syndrome in obese childrenen_US
dc.typeArticleen_US

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