Histopathological Analysis in Testicular Tumors: 10 Years of Experience

Basit Öğe Kaydı
dc.contributor.authorKilinc, Fahriye
dc.contributor.authorTas Aycicek, Seda
dc.contributor.authorEsen, Haci Hasan
dc.date.accessioned2024-02-23T14:27:00Z
dc.date.available2024-02-23T14:27:00Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractIntroduction. This study aims to review the morphological and immunohistochemical features of testicular tumors and compare them with prognostic parameters. Methods. Testicular tumors diagnosed between January 2011 and September 2021 were reviewed. Patient age, tumor subtype, size, spread, lateralization, number of foci, and immunohistochemical results were recorded. Results. A total of 121 tumors were detected, of which 108 (89%) were germ cell tumors (GCTs). Of the germ cell tumors, 70 (65%) were found to be pure type, and 38 (35%) were mixed germ cell tumors. The ratio of pure seminoma among GCTs was 56/108 (52%). Lymphatic/vascular invasion (LVI) was detected in 48/121 (40%), rete testis invasion in 32/121 (26%), hilar soft tissue invasion in 10/121 (8%), epididymal invasion in 5/121 (4%), and spermatic cord invasion in 5/121 (4%) patients. Lymphatic/vascular invasion was observed in 6 (22%) of 27 germ cell tumors smaller than 3 cm in size, and rete testis invasion was observed in 2 (7%), while in 40 (55%) of the 73 germ cell tumors of 3 cm and above, lymphatic/vascular invasion was seen, and 26 (36%) of them had rete testis invasion. Immunohistochemical results contributed significantly to the determination of tumor components and rates, especially in mixed germ cell tumors. Conclusion. Most of the tumors were germ cell tumors, and the majority were seminomas. Lymphatic/vascular invasion and rete testis invasion rates increase as the tumor diameter increases, which is more evident when the 3 cm cut-off value is taken into account (P < 0.005).en_US
dc.identifier.doi10.1177/10668969231180270
dc.identifier.issn1066-8969
dc.identifier.issn1940-2465
dc.identifier.pmid37292006en_US
dc.identifier.scopus2-s2.0-85162997226en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1177/10668969231180270
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14413
dc.identifier.wosWOS:001007536800001en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofInternational Journal Of Surgical Pathologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTestisen_US
dc.subjectGerm Cell Tumoren_US
dc.subjectTesticular Tumoren_US
dc.subjectSeminomaen_US
dc.titleHistopathological Analysis in Testicular Tumors: 10 Years of Experienceen_US
dc.typeArticleen_US

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