Is Turkish coffee protects Drosophila melanogaster on cadmium acetate toxicity by promoting antioxidant enzymes?

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dc.contributor.authorGunes, Eda
dc.contributor.authorSensoy, Erhan
dc.date.accessioned2024-02-23T14:02:25Z
dc.date.available2024-02-23T14:02:25Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractWith their increasing use in today's industry, heavy metals cause biochemical and biophysical changes by affecting the control and regulatory systems of living things. Cadmium (Cd), a heavy metal, spreads to the environment through both natural sources and industrial activities. It is taken into the organism through water, food, skin contact or smoke. Systems and organs of living things are directly or indirectly affected by Cd toxicity. Besides their recreational usage, herbal products such as coffee are preferred in alternative medicine because of their antioxidant, anti-inflammatory, anticancer and antidiabetic effects. Turkish coffee (TK) is a drink rich in flavorings, phenolic compounds and antioxidant compounds. The study evaluated the possible antioxidant role of TK against oxidative stress induced by Cadmium acetate (CdA) in the fat tissues of old-young female individuals of Drosophila melanogaster. The female flies were fed with either a standard diet, or CdA (10-30 mg), or TK (2%), or both (CdA + TK) for 3 and 10 days. Following the completion of the feeding period, the amounts of fatbody and oxidative stress markers (oxidative stress index, malondialdehyde), activities of antioxidant enzymes (Glutathione-S-transferase, Catalase, and Superoxide dismutase) and their levels were measured. Fat body lipid droplets were high in the individuals exposed to high concentrations of CdA. It was determined that lipid droplets decreased but did not significantly alter oxidative stress in the individuals treated with TK (p = 0.05). This article may be of help in terms of the use of TK compounds as antioxidants to evaluate their effects in preventing heavy metal accumulation and stress in the aging process.en_US
dc.identifier.doi10.1016/j.chemosphere.2022.133972
dc.identifier.issn0045-6535
dc.identifier.issn1879-1298
dc.identifier.pmid35192850en_US
dc.identifier.scopus2-s2.0-85125456069en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.chemosphere.2022.133972
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11705
dc.identifier.volume296en_US
dc.identifier.wosWOS:000782648600004en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofChemosphereen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDrosophila Melanogasteren_US
dc.subjectCadmium Acetateen_US
dc.subjectTurkish Coffeeen_US
dc.subjectTotal Oxidation Statusen_US
dc.subjectAgingen_US
dc.subjectPollutionen_US
dc.titleIs Turkish coffee protects Drosophila melanogaster on cadmium acetate toxicity by promoting antioxidant enzymes?en_US
dc.typeArticleen_US

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