Determining the Infectious Pathogens and Their Resistance to Antibiotics in a Pediatric Intensive Care Unit

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dc.contributor.authorAkin, Fatih
dc.contributor.authorYazar, Abdullah
dc.contributor.authorDogan, Metin
dc.date.accessioned2024-02-23T14:16:52Z
dc.date.available2024-02-23T14:16:52Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractIntroduction Nosocomial infections are one of the main causes of morbidity and mortality. It is important to know the common infectious pathogens and their resistance profiles in intensive care units (ICUs) to determine appropriate treatment protocols. The aimof this study was to determine the epidemiological profile of microorganisms isolated in a pediatric ICU (PICU) and to determine antibiotic resistance in isolated strains. Materials and Methods This retrospective study was performed at the Meram Medical Faculty Hospital, Necmettin Erbakan University, Konya, Turkey. A total of 1,502 bacteria that were isolated from various specimens from children who were hospitalized in PICUs between January 2014 and December 2015 were included in this study to determine the isolated bacteria diversity and susceptibility to various antibiotics. Results Staphylococcus spp. was the most frequently isolated microorganism followed by Escherichia coli and Klebsiella spp., respectively. The sites where pathogens were isolated were as follows: 616 blood, (41%), 445 urine (29.6%), 60 sputum (4%), 44 cerebrospinal fluid (2.9%), 25 wound swab (1.6%), 20 tracheal aspirate (1.3%), and 26 others (1.7%). The carbapenem resistance rate was 40.8% among Pseudomonas aeruginosa isolates. Among 60 Acinetobacter baumannii isolates tested, 62% were resistant to carbapenems. Sensitivity rates of A. baumannii isolates to tigecycline and colistin were as high as 98 and 96%, respectively. Meropenem and colistin resistance rates to Klebsiella spp. were 16.2 and 15%, respectively. Conclusion In conclusion, it is essential to identify the infectious pathogens and their resistance to antibiotics especially in ICUs where infections with multidrug-resistant bacteria are frequent. Studies on this issue should be performed at appropriate time intervals.en_US
dc.identifier.doi10.1055/s-0037-1607236
dc.identifier.endpage45en_US
dc.identifier.issn1305-7707
dc.identifier.issn1305-7693
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85031489581en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage42en_US
dc.identifier.urihttps://doi.org/10.1055/s-0037-1607236
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12838
dc.identifier.volume13en_US
dc.identifier.wosWOS:000426303500010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofJournal Of Pediatric Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPediatric Intensive Care Uniten_US
dc.subjectInfectionen_US
dc.subjectResistance Ratesen_US
dc.titleDetermining the Infectious Pathogens and Their Resistance to Antibiotics in a Pediatric Intensive Care Uniten_US
dc.typeArticleen_US

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