Pulmonary embolism and hematologic outcome in cancer patients initiating chemotherapy

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dc.contributor.authorKeskin, S.
dc.contributor.authorGuler, T.
dc.contributor.authorKalkan, H.
dc.contributor.authorKeskin, Z.
dc.contributor.authorOdev, K.
dc.date.accessioned2024-02-23T14:37:41Z
dc.date.available2024-02-23T14:37:41Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractPURPOSE: The aim of this study was to determine the relationship between chemotherapy use and the frequency of pulmonary embolism (PE) and associated mortality, clinical, and biochemical parameters. An additional aim was to analyze computed tomography pulmonary angiography findings. MATERIALS AND METHODS: The study population comprised 65 of 368 consecutive patients diagnosed with PE who underwent chemotherapy in the Medical Oncology Department. The study population had cancer of various origins, including breast, colorectal, lung, gynecological, gastric and pancreatic, lymphatic, and other sites. The patients' clinical records were reviewed for leukocyte and platelet count, mean platelet volume (MPV), neutrophil to lymphocyte ratio, and level of mortality. As the parameters were normally distributed, the correlation coefficients and their significance were calculated using Pearson's test. One-way analysis of variance was used to compare the leukocyte counts among the cancer groups. A t-test was used to compare the means of the platelet and leukocyte counts between the patients. A Chi-square test was used to compare binary outcomes for categorical variables. Patients who died in the 1st year and others (survivors and patients who died after the 1st year) were compared using multinomial logistic regression analysis. RESULTS: When the patients who died in the 1st year and the survivors were compared, there was a statistically significant difference in the platelet count between the two groups. The platelet count, MPV, and leukocyte count of the patients with PE were significantly high. The leukocyte count was also significantly high in patients with breast, colorectal, lung, and gynecological cancers. CONCLUSION: Our results indicate that in cancer patients with PE who undergo chemotherapy, the platelet count, MPV, and leukocyte count are significantly high.en_US
dc.identifier.doi10.4103/0019-509X.146787
dc.identifier.endpage305en_US
dc.identifier.issn0019-509X
dc.identifier.issn1998-4774
dc.identifier.issue3en_US
dc.identifier.pmid25494126en_US
dc.identifier.scopus2-s2.0-84920086695en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage303en_US
dc.identifier.urihttps://doi.org/10.4103/0019-509X.146787
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16201
dc.identifier.volume51en_US
dc.identifier.wosWOS:000347027200022en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIndian Cancer Socen_US
dc.relation.ispartofIndian Journal Of Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCanceren_US
dc.subjectChemotherapyen_US
dc.subjectLeukocytosisen_US
dc.subjectPulmonary Embolismen_US
dc.subjectThrombosisen_US
dc.titlePulmonary embolism and hematologic outcome in cancer patients initiating chemotherapyen_US
dc.typeArticleen_US

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