How effective are the 6 European Society of Immunodeficiency warning signs for primary immunodeficiency disease?

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dc.contributor.authorArslan, Sevket
dc.contributor.authorUcar, Ramazan
dc.contributor.authorCaliskaner, Ahmet Zafer
dc.contributor.authorReisli, Ismail
dc.contributor.authorGuner, Sukru Nail
dc.contributor.authorSayar, Esra Hazar
dc.contributor.authorBaloglu, Ismail
dc.date.accessioned2024-02-23T14:02:05Z
dc.date.available2024-02-23T14:02:05Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractBackground: The European Society of Immunodeficiency (ESID) developed 6 warning signs to promote the awareness of adult primary immunodeficiency disease (PID). Objective: To screen adult patients for the presence of PID using these 6 warning signs to determine the effectiveness of this protocol. Methods: Questions related to the ESID warning signs for adult PID were added to the standard outpatient clinic file system and asked of 3,510 patients who were admitted to our clinic for any reason. Patients with signs and/or suspicion of PID based on their medical history underwent immunologic investigation. Results: In total, 24 patients were diagnosed as having a PID. The most common reason that patients with PID were admitted was frequent infection (n = 18 [75%]), and the most common PID subgroup was common variable immunodeficiency (n = 12 [50%]). Twenty patients with PID had at least one positive finding according to the ESID warning signs. Two patients with gastrointestinal concerns and 2 with dermatologic symptoms were also diagnosed as having a PID, although they did not have any of the ESID warning signs. Conclusion: The ESID warning signs do not specify the need for symptoms to diagnose a PIDs and do not include a comprehensive list of all signs and symptoms of PIDs. As a result, more than infection-centric questions are needed to identify adult patients with immunodeficiencies. (C) 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.anai.2015.12.001
dc.identifier.endpage+en_US
dc.identifier.issn1081-1206
dc.identifier.issn1534-4436
dc.identifier.issue2en_US
dc.identifier.pmid26815708en_US
dc.identifier.scopus2-s2.0-84957797999en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage151en_US
dc.identifier.urihttps://doi.org/10.1016/j.anai.2015.12.001
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11573
dc.identifier.volume116en_US
dc.identifier.wosWOS:000368573000012en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofAnnals Of Allergy Asthma & Immunologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleHow effective are the 6 European Society of Immunodeficiency warning signs for primary immunodeficiency disease?en_US
dc.typeArticleen_US

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