GnRH agonist triggering affects the kinetics of embryo development: a comparative study

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dc.contributor.authorGurbuz, Ali Sami
dc.contributor.authorGode, Funda
dc.contributor.authorUzman, Mehmet Sukru
dc.contributor.authorInce, Betul
dc.contributor.authorKaya, Melek
dc.contributor.authorOzcimen, Necati
dc.contributor.authorOzcimen, Emel Ebru
dc.date.accessioned2024-02-23T14:29:08Z
dc.date.available2024-02-23T14:29:08Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractBackground: To evaluate the effects of an ovulation triggering agent, human chorionic gonadotropin (hCG), versus a gonadotropin-releasing hormone agonist (GnRHa) on early embryo development in vitro using a time-lapse system. Methods: Retrospective analysis of a prospectively collected database. A total of 739 embryos from 152 infertile couples undergoing intracytoplasmic sperm injection cycles. Interventions : Embryo culture in a time-lapse incubator (EmbryoScope, Vitrolife, Goteborg, Sweden). Main Outcome Measures: Embryo morphokinetic parameters. Results: In the 152 women, 252 embryos were derived from GnRHa-triggered cycles compared with 487 embryos derived from hCG-triggered cycles. Time-lapse analysis revealed that embryos from cycles triggered by a GnRHa cleaved faster than embryos derived from hCG-triggered cycles. Conclusion: Triggering with a GnRHa in in vitro fertilization cycles affects embryo kinetics.en_US
dc.identifier.doi10.1186/s13048-016-0229-8
dc.identifier.issn1757-2215
dc.identifier.pmid27059823en_US
dc.identifier.scopus2-s2.0-84964056061en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1186/s13048-016-0229-8
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14551
dc.identifier.volume9en_US
dc.identifier.wosWOS:000373672600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBiomed Central Ltden_US
dc.relation.ispartofJournal Of Ovarian Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAgonist Triggeren_US
dc.subjectOocyteen_US
dc.subjectEmbryo Qualityen_US
dc.subjectTime Lapseen_US
dc.subjectMorphokineticen_US
dc.titleGnRH agonist triggering affects the kinetics of embryo development: a comparative studyen_US
dc.typeArticleen_US

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