The Relationship of Red-Cell Distribution Width and Carotid Intima Media in Chronic Kidney Disease

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dc.contributor.authorGuclu, Aydin
dc.contributor.authorTokmak, Turgut Tursem
dc.contributor.authorKaymaz, Haci
dc.contributor.authorTurkmen, Kultigin
dc.contributor.authorSenol, Hande
dc.contributor.authorOzhan, Nail
dc.contributor.authorDursun, Yusuf
dc.date.accessioned2024-02-23T14:41:25Z
dc.date.available2024-02-23T14:41:25Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractOBJECTIVE: Red-cell distribution width (RDW) is a parameter routinely used for diagnosis of different anemia types. Recent studies have shown the RDW relationship with mortality in general population and patients with cardiovascular disease. However, the number of studies on RDW in chronic kidney disease (CKD) is insufficient. We evaluated the relationship between RDW and carotid intima media thickness (IMT), which is a predictor of atherosclerosis, in patients with CKD. MATERIAL and METHODS: 30 healthy controls, 30 patients with CKD, 37 hemodialysis patients were included. IMT was measured with ultrasonography. RESULTS: We identified statistically significant differences in CRP (p: 0.039), hemoglobin (p< 0.001), IMK (p< 0.001), RDW (p< 0.001), urea (p< 0.001), creatinine (p< 0.001), albumin (p< 0.001), uric acid (p< 0.001) and ferritin (p< 0.001) levels among three groups. In post hoc analysis, the IMK value was statistically significantly higher in the predialysis (p< 0.001) and hemodialysis group than healthy controls. IMK value was not statistically different in the hemodialysis group than the predialysis group (p: 0.988). The RDW value was higher in the predialysis group than controls with a trend to statistical significance (p: 0.067). RDW value showed positive correlation with IMK (r: 0.356 P: 0.012) and CRP (r: 0.361 P: 0.004). CONCLUSION: RDW is associated with inflammation and intima media thickness in patients with CKD.en_US
dc.identifier.doi10.5262/tndt.2016.1002.11
dc.identifier.endpage191en_US
dc.identifier.issn1300-7718
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84969821539en_US
dc.identifier.startpage187en_US
dc.identifier.urihttps://doi.org/10.5262/tndt.2016.1002.11
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16846
dc.identifier.volume25en_US
dc.identifier.wosWOS:000393291900011en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurk Nefroloji Diyaliz Transplantasyon Dergisien_US
dc.relation.ispartofTurkish Nephrology Dialysis And Transplantation Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRdwen_US
dc.subjectAtherosclerosisen_US
dc.subjectChronic Kidney Diseaseen_US
dc.titleThe Relationship of Red-Cell Distribution Width and Carotid Intima Media in Chronic Kidney Diseaseen_US
dc.typeArticleen_US

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