Yazar "Belviranli, Metin" seçeneğine göre listele
Listeleniyor 1 - 6 / 6
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Effectiveness of collagenase in preventing postoperative intra-abdominal adhesions(Elsevier Science Bv, 2013) Cakir, Murat; Tekin, Ahmet; Kucukkartallar, Tevfik; Yilmaz, Huseyin; Belviranli, Metin; Kartal, AdilIntroduction: The purpose of this study is to investigate the effectiveness of Collagenase clastridiopeptidase an enzyme preparation used in enzymatic debridement in preventing adhesions brought about by peritoneal damage. Methods: The study covers a total of 40 rats in 4 groups each having 10 rats. Group 1: The control group. Group 2: Normal saline group. Group 3: Sterile Novuxol (R) group. Group 4: The group where the intraperitoneal and systemic effects of sterile Novuxol (R) were investigated. Adhesion frequency and grades were scored on the post-op 11th day according to Granat. Blood work including hemoglobin, aspartate aminotransferase, alanine aminotransferase, urea, creatinine, and albumin level measurements were performed. Toxicity was investigated histopathologically through samples taken from the liver and the peritoneum from Group 4. Results: Adhesion frequency was found to be 80% on the right and 90% on the left for Group 1, while it was 50% on both left and right for Group 2, and 30% on the right and 10% on the left for Group 3. Adhesion stages were found to be 1: 2.35 +/- 1.42 for Group 1, 0.31 +/- 1.15 for Group 2, and 0.20 +/- 0.41 for Group 3. Adhesion stage of the Sterile Novuxol (R) Group was lower than all the other groups (p < 0.05). Biochemical and hematological parameters were similar in all groups (p > 0.05). Histopathological analysis revealed no hepatotoxicity. Conclusions: According to the results of our study, we believe that Sterile Novuxol (R) can be a good anti-adhesive agent considering its ease of use, non-toxicity, and effectiveness. (C) 2013 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.Öğe New surgical technique applied with urological instruments in bilobar multiple hepatolithiasis: Ultra-mini percutaneous hepatolithotomy(Aves, 2017) Ozturk, Ahmet; Sonmez, Mehmet Giray; Bakdik, Suleyman; Goger, Yunus Emre; Ozkent, Mehmet Serkan; Aksoy, Faruk; Belviranli, MetinIntrahepatic bile duct stones may emerge with manifestations as chronic stomach ache, cholestasis, cholangitis, abscess, post-obstructive atrophy and liver cirrhosis presentation may occur. Thus the treatment of symptomatic hepatolithiasis patients should be provided. Different methods such as biliary decompression, endoscopic, percutaneous or open surgery are recommended for the treatment of patients with intrahepatic gallstones. The aim of the treatment is to extract the stones and regain biliary drainage. But the treatment regimen to be applied should be determined after examining the age, performance condition, general condition of the patient and location of the stone carefully. In this case, we presented a young female patient who had many unsuccessful surgical interventions due to coledochal cyst and congenital malformation in bile ducts, had large stones in right and left intrahepatic bile ducts and in whom we provided complete stone-free condition through Ultra-Mini Percutaneous Hepatolithotomy (UM-PHL) using urological instruments.Öğe Primer anorektal malign melanom: 5 Yıllık tek merkez deneyimi(2013) Çakır, Murat; Küçükkartallar, Tevfik; Tekin, Ahmet; Belviranli, MetinAmaç: Gastrointestinal sistemde Malign Melanom beklenmedik bir durumdur fakat nadir değildir. Primer Malign melanom anorektol bölgede nadir görülür. Uzun dönem yaşam beklentisi nadirdir. Çoğu hasta tedavi edilemeyen sistemik hastalık nedeniyle kaybedilmektedir. Bu çalışmada Malign Melanomla ilgili klinik deneyimlerimizi aktararak, tanı ve tedavisi ile ilgili güncel literatür bilgilerini paylaşmayı amaçladık. Materyal ve metot: 2006-2011 tarihleri arasında cerrahi girişimde bulunulan ve patolojik tanısı Malign Melanom olan 10 olgu retrospektif olarak incelendi. Hastalar yaş, cinsiyet, klin görünüm, metastaz varlığı, immünhistokimyasal özelliği, takip süreleri ve uygulanan cerrahi girişimin açısından değerlendirildi. Bulgular: Hastaların 4'ü kadın, 6'si erkek olup yaş ortalaması 67,7 (50-83)' idi. Beş hastada cerrahi tedavi ile kür sağlandı. Dört hasta inoperable olarak tespit edildi. Tüm vakalarda S-100 pozitifti. Hastalar ortalama 15 (5-24) ay takip edildi. Sonuçlar: Primer anorektal malign melanom, anorektal tümörlerin ayırıcı tanısında nadir bir nedendir. Tercih edilen tedavi seçeneği cerrahidir. Palyatif amaçlı kemoterapi ve immünoterapi kullanılır. Tedavi yöntemlerindeki gelişmelere rağmen, bu tümörün prognozu halen kötüdür.Öğe Role of thiol-disulfide hemostasis in early diagnosis of acute mesentery ischemia: An experimental study(Turkish Assoc Trauma Emergency Surgery, 2022) Yildirim, Mehmet Aykut; Kocabas, Rahim; Kilinc, Ibrahim; Simsek, Gurcan; Senturk, Mustafa; Cakir, Murat; Belviranli, MetinBACKGROUND: Acute mesenteric ischemia (AMI) is a rarely observed acute abdominal disease that may be mortal and is difficult to diagnose early. The aim of our study is to assess the role of Thiol-Disulphide Haemostasis (TDH), a new method for AMI which still has no specific biochemical markers for early diagnosis, and to assess it together with Ischemia-Modified Albumin (IMA) which METHODS: The study included 32 Wistar albino rats in four groups. The 1st group (n=8) was the control group, 2nd group (n=8) was the sham group, 3rd group (n=8) had 3 h of arterial mesentery ischemia and the 4th group (n=8) had 6 h of arterial mesentery ischemia. RESULTS: In the 3rd and 6th h, serum total thiol and native thiol values significantly reduced (p<0.001), while serum disulfide, IMA, and lactate values clearly increased (p<0.001). Serum thiol values were observed to reduce from the 1st h. CONCLUSION: TDH changes in the early period of AMI. The TDH parameters can be used with IMA as diagnostic parameters for patients with suspected AMI in the early period.Öğe Role of thiol-disulfide hemostasis in early diagnosis of acute mesentery ischemia: An experimental study(Turkish Assoc Trauma Emergency Surgery, 2022) Yildirim, Mehmet Aykut; Kocabas, Rahim; Kilinc, Ibrahim; Simsek, Gurcan; Senturk, Mustafa; Cakir, Murat; Belviranli, MetinBACKGROUND: Acute mesenteric ischemia (AMI) is a rarely observed acute abdominal disease that may be mortal and is difficult to diagnose early. The aim of our study is to assess the role of Thiol-Disulphide Haemostasis (TDH), a new method for AMI which still has no specific biochemical markers for early diagnosis, and to assess it together with Ischemia-Modified Albumin (IMA) which METHODS: The study included 32 Wistar albino rats in four groups. The 1st group (n=8) was the control group, 2nd group (n=8) was the sham group, 3rd group (n=8) had 3 h of arterial mesentery ischemia and the 4th group (n=8) had 6 h of arterial mesentery ischemia. RESULTS: In the 3rd and 6th h, serum total thiol and native thiol values significantly reduced (p<0.001), while serum disulfide, IMA, and lactate values clearly increased (p<0.001). Serum thiol values were observed to reduce from the 1st h. CONCLUSION: TDH changes in the early period of AMI. The TDH parameters can be used with IMA as diagnostic parameters for patients with suspected AMI in the early period.Öğe Use the bipolar forceps in thyroid surgery(Excerpta Medica Inc-Elsevier Science Inc, 2018) Yildirim, Mehmet Aykut; Kartal, Adil; Belviranli, Metin; Simsek, Gurcan[Abstract Not Availabe]
