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    Anaesthetic Management with Thromboelastography in a Patient with Glanzmann Thrombasthenia
    (Aves, 2014) Topal, Ahmet; Kilicaslan, Alper; Erol, Atilla; Cankaya, Baris; Otelcioglu, Seref
    Glanzmann thrombastenia (GT) is a rare disease of an autosomal recessive inheritance characterized with fatal bleeding tendency. The anaesthesiologist should be cognizant of the risk involved and be prepared with necessary measures. In this paper, we present a GT case of a 9-year-old male with hypospadias, which was successfully repaired after platelet transfusions according to the thromboelastography tracings.
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    Olanzapine-Induced Malignant Neuroleptic Syndrome
    (Aves, 2014) Saritas, Tuba Berra; Cankaya, Baris; Yosunkaya, Alper
    Neuroleptic malignant syndrome (NMS), caused by antipsychotic therapy, shows itself with mental status alteration, high fever, autonomic dysfunction, and muscle rigidity. It is a rare idiosyncratic reaction with mortality risk. The etiology is still unknown. NMS- related mortality and morbidity can be decreased by cessation of the used drug and aggressive treatment. Olanzapine is a thienobenzodiazepine, a member of atypical antipsychotic drugs; its structure and effects on neurotransmitters resemble clozapine. Here we report a case of bipolar disorder receiving olanzapine therapy for 10 years, who developed NMS without rigidity. We emphasized the importance of early hydration and hemodiafiltration therapy.