Olanzapine-Induced Malignant Neuroleptic Syndrome
Küçük Resim Yok
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aves
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Neuroleptic malignant syndrome (NMS), caused by antipsychotic therapy, shows itself with mental status alteration, high fever, autonomic dysfunction, and muscle rigidity. It is a rare idiosyncratic reaction with mortality risk. The etiology is still unknown. NMS- related mortality and morbidity can be decreased by cessation of the used drug and aggressive treatment. Olanzapine is a thienobenzodiazepine, a member of atypical antipsychotic drugs; its structure and effects on neurotransmitters resemble clozapine. Here we report a case of bipolar disorder receiving olanzapine therapy for 10 years, who developed NMS without rigidity. We emphasized the importance of early hydration and hemodiafiltration therapy.
Açıklama
Anahtar Kelimeler
Neuroleptic Malignant Syndrome, Olanzapine, Rigidity, Hemodiafiltration
Kaynak
Turkish Journal Of Anaesthesiology And Reanimation
WoS Q Değeri
Scopus Q Değeri
Cilt
42
Sayı
5
