Olanzapine-Induced Malignant Neuroleptic Syndrome

dc.contributor.authorSaritas, Tuba Berra
dc.contributor.authorCankaya, Baris
dc.contributor.authorYosunkaya, Alper
dc.date.accessioned2024-02-23T14:41:15Z
dc.date.available2024-02-23T14:41:15Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractNeuroleptic malignant syndrome (NMS), caused by antipsychotic therapy, shows itself with mental status alteration, high fever, autonomic dysfunction, and muscle rigidity. It is a rare idiosyncratic reaction with mortality risk. The etiology is still unknown. NMS- related mortality and morbidity can be decreased by cessation of the used drug and aggressive treatment. Olanzapine is a thienobenzodiazepine, a member of atypical antipsychotic drugs; its structure and effects on neurotransmitters resemble clozapine. Here we report a case of bipolar disorder receiving olanzapine therapy for 10 years, who developed NMS without rigidity. We emphasized the importance of early hydration and hemodiafiltration therapy.en_US
dc.identifier.doi10.5152/TJAR.2014.46704
dc.identifier.endpage291en_US
dc.identifier.issn2667-6370
dc.identifier.issue5en_US
dc.identifier.pmid27366439en_US
dc.identifier.scopus2-s2.0-84907047911en_US
dc.identifier.startpage288en_US
dc.identifier.urihttps://doi.org/10.5152/TJAR.2014.46704
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16763
dc.identifier.volume42en_US
dc.identifier.wosWOS:000218636000012en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherAvesen_US
dc.relation.ispartofTurkish Journal Of Anaesthesiology And Reanimationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNeuroleptic Malignant Syndromeen_US
dc.subjectOlanzapineen_US
dc.subjectRigidityen_US
dc.subjectHemodiafiltrationen_US
dc.titleOlanzapine-Induced Malignant Neuroleptic Syndromeen_US
dc.typeArticleen_US

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