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    Comparison of maternal and perinatal outcomes of pregnancies with frozen and fresh embryo transfers at term pregnancy Frozen and fresh embryo transfer results
    (Bayrakol Medical Publisher, 2022) Horasanli, Jule Eric; Energin, Hasan; Ferlibas, Enes
    Aim : In our study, we aimed to compare maternal and perinatal outcomes of frozen and fresh embryo transfers, induced by single or double embryo transfer with in vitro fertilization (IVF) at term pregnancy. Material and Methods: After obtaining ethics, our study was performed retrospectively assessing pregnancies in women between the ages of 18 and 40 induced with single or double embryo transfer with IVF between the years 2010 and 2020. Maternal outcomes such as oligohydramnios, polyhydramnios, preeclampsia, placenta previa, placenta accreta syndrome (PAS). and hysterectomy were examined in all groups. Perinatal outcomes including birth weight, time of delivery, small for gestational age (SGA), large for gestational age (LGA), appropriate for gestational age (AGA), preterm labor, Apgar score of infant at five minutes, and intensive care requirement were also investigated. Results: No difference was observed in terms of oocyte number collected, neonatal intensive care requirement. Apgar scores. postpartum hysterectomy, and blood transfusions. There was no difference between the groups in birth weight, preterm labor, and delivery time. There was no significant difference between the groups in SGA, LGA, and AGA. Polyhydramnios and oligohydramnios were significantly higher in the fresh transfer group (p - 0.006 and p - 0.006, respectively). Among perinatal parameters, the frequency of placenta previa was significantly higher in the frozen transfer group (p - 0.001). The frequency of placenta accreta and preeclampsia was not significantly different. Discussion: Placenta previa was higher in the frozen transfer group, suggesting frozen embryo transfer increases the risk of placenta previa. Oligohydramnios and polyhydramnios were higher in the fresh transfer group.
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    Does mild thrombocytopenia increase peripartum hemorrhage in elective cesarean deliveries? A retrospective cohort study
    (Wiley, 2021) Isikalan, Mehmet Murat; Ozkaya, Eren Berkay; Ozkaya, Busra; Ferlibas, Enes; Sengul, Nurullah; Acar, Ali
    ObjectiveTo investigate the effect of mild thrombocytopenia (platelet count: 100 000-149 000/mu l) on peripartum hemorrhage in elective cesarean deliveries. MethodsThis study was conducted between January 2018 and May 2019 in a hospital, located in Konya, Turkey. Uncomplicated pregnancies undergoing elective cesarean section were included. Of 1992 eligible patients, 201 women were determined as the mild thrombocytopenia group, 48 women as the severe thrombocytopenia group, and 1743 women as the control group. The estimated blood loss volume (EBLV), the need for blood transfusion, and excessive blood loss rates were compared among groups. Logistic regression analysis was performed for potential confounding factors. ResultsThe EBLV and excessive blood loss ratios were significantly higher in the mild thrombocytopenia group compared with the control group (P < 0.001 and P < 0.05, respectively). There was no significant difference between the mild thrombocytopenia and control groups in terms of the number of patients receiving a blood transfusion. The probability of excessive blood loss was significantly higher in the mild thrombocytopenia group, even after adjusting the odds ratio for confounding factors (adjusted odds ratio 1.94, 95% confidence interval 1.27-2.95, P = 0.002). ConclusionMild thrombocytopenia appears to increase the likelihood of peripartum hemorrhage in elective cesarean deliveries in uncomplicated pregnancies. Mild thrombocytopenia can increase estimated blood loss volume and the rate of excessive blood loss in elective cesarean operations.
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    Does wearing double surgical masks during the COVID-19 pandemic reduce maternal oxygen saturation in term pregnant women?: A prospective study
    (Springer Heidelberg, 2022) Isikalan, Mehmet Murat; Ozkaya, Busra; Ozkaya, Eren Berkay; Gumus, Meryem; Ferlibas, Enes; Acar, Ali
    Purpose This study aimed to compare the effects of using single and double surgical masks (SM) on maternal oxygen saturation in pregnant women. Methods In this prospective study, single or double SM were worn by term pregnant women who applied for routine controls. The vital signs of the participants such as oxygen saturation, pulse, respiratory rate, fever, systolic and diastolic blood pressure were measured at admission and 30 min later. Results There were 223 participants in the single SM group and 231 participants in the double SM group. Thirty minutes after putting on the mask, there was no significant difference in the proportion of patients whose oxygen saturation fell below 95 (3.6 vs 5.6%, p = 0.301). No significant difference was observed between the admission and 30 min oxygen saturation levels of the pregnant women in the single SM group. However, maternal oxygen saturation after 30 min of the pregnant women in the double SM group was significantly lower (97.4 +/- 1.1 vs 96.6 +/- 1.3, p < 0.001). No significant changes were observed in the vital signs of either groups. Conclusion When using double SM, oxygen saturation is significantly reduced compared to pre-mask values. Nevertheless, it seems difficult to say that these decreases have clinical significance.