Does mild thrombocytopenia increase peripartum hemorrhage in elective cesarean deliveries? A retrospective cohort study

Küçük Resim Yok

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Wiley

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

ObjectiveTo investigate the effect of mild thrombocytopenia (platelet count: 100 000-149 000/mu l) on peripartum hemorrhage in elective cesarean deliveries. MethodsThis study was conducted between January 2018 and May 2019 in a hospital, located in Konya, Turkey. Uncomplicated pregnancies undergoing elective cesarean section were included. Of 1992 eligible patients, 201 women were determined as the mild thrombocytopenia group, 48 women as the severe thrombocytopenia group, and 1743 women as the control group. The estimated blood loss volume (EBLV), the need for blood transfusion, and excessive blood loss rates were compared among groups. Logistic regression analysis was performed for potential confounding factors. ResultsThe EBLV and excessive blood loss ratios were significantly higher in the mild thrombocytopenia group compared with the control group (P < 0.001 and P < 0.05, respectively). There was no significant difference between the mild thrombocytopenia and control groups in terms of the number of patients receiving a blood transfusion. The probability of excessive blood loss was significantly higher in the mild thrombocytopenia group, even after adjusting the odds ratio for confounding factors (adjusted odds ratio 1.94, 95% confidence interval 1.27-2.95, P = 0.002). ConclusionMild thrombocytopenia appears to increase the likelihood of peripartum hemorrhage in elective cesarean deliveries in uncomplicated pregnancies. Mild thrombocytopenia can increase estimated blood loss volume and the rate of excessive blood loss in elective cesarean operations.

Açıklama

Anahtar Kelimeler

Elective Cesarean Delivery, Mild Thrombocytopenia, Platelets, Postpartum Hemorrhage

Kaynak

International Journal Of Gynecology & Obstetrics

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

153

Sayı

1

Künye