Does mild thrombocytopenia increase peripartum hemorrhage in elective cesarean deliveries? A retrospective cohort study

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dc.contributor.authorIsikalan, Mehmet Murat
dc.contributor.authorOzkaya, Eren Berkay
dc.contributor.authorOzkaya, Busra
dc.contributor.authorFerlibas, Enes
dc.contributor.authorSengul, Nurullah
dc.contributor.authorAcar, Ali
dc.date.accessioned2024-02-23T12:11:10Z
dc.date.available2024-02-23T12:11:10Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractObjectiveTo investigate the effect of mild thrombocytopenia (platelet count: 100 000-149 000/mu l) on peripartum hemorrhage in elective cesarean deliveries. MethodsThis study was conducted between January 2018 and May 2019 in a hospital, located in Konya, Turkey. Uncomplicated pregnancies undergoing elective cesarean section were included. Of 1992 eligible patients, 201 women were determined as the mild thrombocytopenia group, 48 women as the severe thrombocytopenia group, and 1743 women as the control group. The estimated blood loss volume (EBLV), the need for blood transfusion, and excessive blood loss rates were compared among groups. Logistic regression analysis was performed for potential confounding factors. ResultsThe EBLV and excessive blood loss ratios were significantly higher in the mild thrombocytopenia group compared with the control group (P < 0.001 and P < 0.05, respectively). There was no significant difference between the mild thrombocytopenia and control groups in terms of the number of patients receiving a blood transfusion. The probability of excessive blood loss was significantly higher in the mild thrombocytopenia group, even after adjusting the odds ratio for confounding factors (adjusted odds ratio 1.94, 95% confidence interval 1.27-2.95, P = 0.002). ConclusionMild thrombocytopenia appears to increase the likelihood of peripartum hemorrhage in elective cesarean deliveries in uncomplicated pregnancies. Mild thrombocytopenia can increase estimated blood loss volume and the rate of excessive blood loss in elective cesarean operations.en_US
dc.identifier.doi10.1002/ijgo.13554
dc.identifier.endpage94en_US
dc.identifier.issn0020-7292
dc.identifier.issn1879-3479
dc.identifier.issue1en_US
dc.identifier.pmid33341932en_US
dc.identifier.scopus2-s2.0-85101047185en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage89en_US
dc.identifier.urihttps://doi.org/10.1002/ijgo.13554
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10571
dc.identifier.volume153en_US
dc.identifier.wosWOS:000616792400001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal Of Gynecology & Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElective Cesarean Deliveryen_US
dc.subjectMild Thrombocytopeniaen_US
dc.subjectPlateletsen_US
dc.subjectPostpartum Hemorrhageen_US
dc.titleDoes mild thrombocytopenia increase peripartum hemorrhage in elective cesarean deliveries? A retrospective cohort studyen_US
dc.typeArticleen_US

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