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  • Küçük Resim
    Öğe
    Primary hiperplastic persistant vitreus
    (2013) Güler, İbrahim; Sakarya, Mehmet Emin; Küçükapan, Ahmet; Özbiner, Hüseyin; Samur, Çiğdem
    Persistent hyperplastic primary vitreous (PHPV) is a disorder of ocular development which occurs due to incomplete regression of the embryonic vitreous and hyaloid vasculature. Most cases of PHPV are sporadic and unilateral. We report a case of PHPV in a 5-year-old male who presented with complaint of decreasing eye size. Grey-scale ultrasonography (US) evaluation revealed an hypoechogenic band in the posterior segment of the left globe extending from the posterior surface of the lens capsule to the optic disc. Also magnetic resonance imaging (MRI) findings suggested the diagnosis of persistent hyperplastic primary vitreous.
  • Küçük Resim
    Öğe
    Splenic artery embolization with Ankaferd blood stopper in a sheep model
    (2016) Koç, Osman; Acar, Kadir; Orhan, Özbek; Güler, İbrahim; Sarıtaş, Kadir; Erdem, Tuba Berra; Toy, Hatice; Gaipov, Abduzhappar; Haznedaroğlu, İbrahim C.
    PURPOSE Splenic artery embolization is a minimally invasive therapeutic procedure utilized in a number of disorders. Ankaferd blood stopper (ABS) is a novel hemostatic agent with a new mechanism of action independent of clotting factors. We aimed to investigate the safety and efficiency of ABS for splenic artery embolization in a sheep model. METHODS Seven adult female sheep were included in the study. Selective celiac angiography was performed using a 5F diagnostic catheter and then a 2.7F hydrophilic coating microcatheter was advanced coaxially to the distal part of the main splenic artery. Under fluoroscopic guidance, 6 mL mixture composed of half-and-half ABS and contrast agent was slowly injected. Fluoroscopy was used to observe the deceleration and stagnation of the flow. Control celiac angiograms were obtained immediately after the embolization. After the procedure, the animals were observed for one day and then sacrificed with intravenous sodium thiopental. RESULTS Technical success rate was 100%. None of the animals died or experienced a major systemic adverse event during the procedure. All of the spleens appeared dark on macroscopic examination due to excessive thrombosis. Microscopically, the majority of the splenic sinusoids (90%-95%) were necrotic. CONCLUSION In our study, splenic artery embolization by ABS was found to be safe and effective in the shortterm. Further studies are needed to better understand the embolizing potential of this novel hemostatic agent.