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Öğe Acute-Phase Stroke Outcome and Lipids(Kare Publ, 2021) Tokgoz, Osman Serhat; Guney, Figen; Kaya, Ahmet; Bugrul, Ahmet; Eruyar, Esra; Buyukgol, Huseyin; Seyithanoglu, AbdullahObjectives: The aim of the study is to investigate the relationship of lipid subgroups with short-term mortality in acute stroke (AS). Methods: This retrospective study included 698 patients with AS who presented within 24 h of symptom onset. A hemogram from peripheral venous blood samples was taken at admission. Total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low- density lipoprotein cholesterol (LDL- C), TC/HDL-C rate, and TG/HDL-C rate were recorded. Duration of follow-up was defined as 30 days. Results: 64 out of 698 patients died during the follow-up period. The mean TG, TG/HDL-C, and TC/HDL-C levels were significantly lower in the mortality group than the survival group. In the receiver operating characteristic (ROC) analysis, the cutoff values and area under the curve of the TG, TG/HDL-C, TC, and TC/HDL- C levels for short-term stroke mortality are as follows ([100.2 mg/dL, 0.648]; [2.52, 0.650]; [170.50 mg/dL, 0.598]; and [4.32, 0.640], respectively). In the Cox regression model, only TG and TG/HDL-C, according to their ROC cutoff values, were independent variables as short-term mortality predictors ( TG =100.2 mg/dL, HR:2.413, 95% CI: 1.345-4.327, P:0.004); ( TG/HDL =2.56, HR: 2.720, 95% CI: 1.389-5.359, P:0.003, respectively). Conclusion: Dyslipidemia is a well-known as a risk factor of stroke. However, this study focused on the estimation that lower TG and TG/HDL-C levels at the time of hospital admission might be predictors of short-term mortality within a month of AS attack, which is a different subject from long term risk factors of stroke. Serum TG level may be a better indicator for mortality in the acute hypercatabolic trauma such as stroke.Öğe Acute-Phase Stroke Outcome and Lipids(Kare Publ, 2021) Tokgoz, Osman Serhat; Guney, Figen; Kaya, Ahmet; Bugrul, Ahmet; Eruyar, Esra; Buyukgol, Huseyin; Seyithanoglu, AbdullahObjectives: The aim of the study is to investigate the relationship of lipid subgroups with short-term mortality in acute stroke (AS). Methods: This retrospective study included 698 patients with AS who presented within 24 h of symptom onset. A hemogram from peripheral venous blood samples was taken at admission. Total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low- density lipoprotein cholesterol (LDL- C), TC/HDL-C rate, and TG/HDL-C rate were recorded. Duration of follow-up was defined as 30 days. Results: 64 out of 698 patients died during the follow-up period. The mean TG, TG/HDL-C, and TC/HDL-C levels were significantly lower in the mortality group than the survival group. In the receiver operating characteristic (ROC) analysis, the cutoff values and area under the curve of the TG, TG/HDL-C, TC, and TC/HDL- C levels for short-term stroke mortality are as follows ([100.2 mg/dL, 0.648]; [2.52, 0.650]; [170.50 mg/dL, 0.598]; and [4.32, 0.640], respectively). In the Cox regression model, only TG and TG/HDL-C, according to their ROC cutoff values, were independent variables as short-term mortality predictors ( TG =100.2 mg/dL, HR:2.413, 95% CI: 1.345-4.327, P:0.004); ( TG/HDL =2.56, HR: 2.720, 95% CI: 1.389-5.359, P:0.003, respectively). Conclusion: Dyslipidemia is a well-known as a risk factor of stroke. However, this study focused on the estimation that lower TG and TG/HDL-C levels at the time of hospital admission might be predictors of short-term mortality within a month of AS attack, which is a different subject from long term risk factors of stroke. Serum TG level may be a better indicator for mortality in the acute hypercatabolic trauma such as stroke.Öğe Adrenal İnsidentalomalı Hastalarda Metabolik Parametreler(2015) Turan, Elif; Kulaksızoğlu, Mustafa; Karakurt, Feridun; Kaya, AhmetAmaç: İnsidental olarak tespit edilen adrenal kitlesi olan hastalarda metabolik durumu belirlemek. Gereç ve Yöntemler: Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Endokrinoloji ve Metabolizma Hastalıkları Bilim dalında Ocak 2010 ve Şubat 2014 tarihleri arasında yatırılarak fonksiyonel tarama yapılan adrenal insidentaloması olan 67 hasta çalışmaya dahil edildi. Bulgular: 67 hastanın 34ü erkek, 33ü kadındı. Hastaların yaş ortalaması 57.1 12, tüm hastaların vücut kütle indeksi 29.16 kg/m2 idi. Çalışmaya dahil edilen hastalara fonksiyonel tarama olarak; Cushing Sendromu, feok- romasitoma ve primer hiperaldesteronizme yönelik tarama testleri uygulandı. 67 hastanın 8 tanesi fonksiyone olarak (6 feokromasitoma, 1 Cushing Sendromu, 1 primerhiperaldesteronizm) tespit edildi. Hastaların 38 tane- sinde bozulmuş açlık glikozu veya tip 2 Diabetes Mellitus tespit edildi. Tüm hastaların ortalama glukoz değeri 127.618 mg/dl, fonksiyone olmayan hastaların ortalama glukozu 12962 mg/dl, fonksiyone olan hastaların glukoz ortalaması ise 117.232 mg/dl olarak ölçüldü. Tüm hastalarda sistolik kan basıncı 12518 mm/Hg, dias- tolik kan basıncı ise 7710.9 mm/Hg olarak ölçüldü. Fonksiyone hastaların ortalama sistolik basıncı 13510.4 mm/Hg iken, fonksiyone olmayan hastalarda 12419 mm/Hg tespit edildi. Tüm hastaların trigliserit, HDL, LDL kolesterol ölçümleri alındı. Sırasıyla ortalama değerleri; 157.583 mg/dl (normal 150mg/dl), 39.39.5 mg/dl (normal 40mg/dl), 120.137 mg/dl (normal 100mg/dl) bulundu. Sonuç: Çalışmamızda sürrenal insidentaloma hastalarının % 56sında insülin direncini gösteren bozulmuş açlık glukozu ve Tip 2 DM tespit edilmiştir. Klinik olarak fonksiyonel olmayan adrenal adenomların neden olduğu hafif kortizol fazlalığı tam olarak cushingoid görüntü gelişmesi için yeterli değilse de, insülin direnci ve bunun klinik sonuçlarına neden olabilmektedir. Bu artmış vücut kütle indeksi ve/veya insidentalomalı hastalarda subk- linik cushing sendromu sıklığı ile de ilişkili olabilir.Öğe Diabetik hastalarda bel ve boyun çevresi ölçümü ile glukoz, lipid ve HBA1C parametreleri arasındaki ilişki(2015) Turan, Elif; Savut, Bülent; Kulaksızoğlu, Mustafa; Uyar, Mehmet; Turan, Yaşar; Kaya, AhmetAmaç: Diyabet olan hastalarda bel çevresi ve boyun çevresinin; glukoz, HBA1c lipid parametreleri ve kan basıncı üzerine etkisini tespit etmek. Gereç ve Yöntemler: Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Endokrinoloji Kliniğine son 6 ayda başvuran 264 Tip 2 Diabetes Mellitus tanısı olan hasta çalışmaya dahil edildi. Bu hastaların kan basıncı, boy, kilo, bel çevresi ve boyun çevresi (BÇ) ölçüldü. Ölçüm sonuçları ile açlık plazma glukoz (APG), A1c lipid para- metreleri ve kan basıncı arasında verilerin korelasyonuna bakıldı. Bulgular: Çalışmaya alınan 264 hastanın 141i (%53.4) kadın, 123i (%46.6) erkekti. Hastaların ortalama yaş 55.7 10, VKİ 31.1 5.5 kg/m2, A1c %8.72.4, APG 18182 mg/dL, trigliserit 182111.7 mg/dL, HDL 42.911.7 mg/dL, LDL 111.834 mg/dL, sistolik kan basıncı (SKB) 13120 mmHg, diastolik kan basıncı (DKB) 81.612 mmHg, kadında bel çevresi ortalama 10614 cm, BÇ 36.22.8 cm, erkekte bel çevresi ortalama 105.912.8 cm, BÇ 37.95.1 cm olarak ölçüldü. Kadınlarda ve erkeklerde ayrı ayrı analizde BKİ ile bel çevresi, BÇ, SKB, DKB arasında anlamlı pozitif korelasyon bulundu (her biri için p0.001). Hem kadında hem erkekte boyun çevresi ile SKB, DKB trigliseritte pozitif korelasyon (sırasıyla p0.001, p0.001, p0.02) tespit edilirken, boyun çevresi ve HDL arasında negatif yönde korelasyon bulundu (p0.09). Kadın ve erkekler diyabetik hastalarda bel çevresi ile SKB ve DKB arasında pozitif korelasyon varken (sırasıyla p0.001, p0.001) ve HDL arasında negatif yönde korelasyon tespit edildi (p0.049). Bel çevresi ve boyun çevresi A1C, APG ve LDL-kolesterol arasında korelasyon tespit edilmedi. Sonuç: Bel çevresinin yanında boyun çevresi ölçümü takibi diyabetik hastalarda metabolik değişiklikleri yan- sıtan önemli ve basit fizik muayene bulgusu olarak kullanılabilir.Öğe Differentiated Thyroid Papillary Carcinoma with Cerebellar Metastasis: A Case Report(2017) Turan, Elif; Kaya, Ahmet; Kulaksızoğlu, Mustafa; Zamani, Ayşe Gül; Kozacıoğlu, SümeyyeDiferansiye tiroid kanseri (DTK) genellikle iyi prognozlu ve uzun sureli sağkalıma sahiptir. DTK'nin uzak metastaz oranı 5-15%'dir. Major uzak metastaz alanları akciğer ve kemiklerdir. Serebrum, meme, karaciğer, böbrek, kas ve deri metastazları çok nadirdir. Tiroid papiller karsinomasının (PTK) moleküler mekanizmalarının incelenmesi, BRAFV600E gen mutasyonunun bu hastalık sürecinde önemini ortaya koymuştur. Tiroid papiller kanserlerindeki bu mutasyonlar, ekstratidroidal yayılım, lenf nodu metastazı, tümör rekürrensi ve mortalite ile ilişkilidir. Biz bu olguda akciğer, kemik, karaciğer, adrenal ve serebellar metastazı olan, BRAF mutasyonunun pozitif, PTK'li 55 yaşında erkek hasta sunduk. DTK'de serebrum metaztazı oldukça nadir görülmektedir. Uzak metaztazlar tutulan alana göre farklı semptomlar gösterebilir. Pozitif BRAFV600E gen mutasyonu PTK'li hastalarda agresif seyir açısından fikir verebilirÖğe Do We Need to Replace GH to Correct Anemia in Hypopituitarism?(Endocrine Soc, 2014) Kulaksizoglu, Mustafa; Ipekci, Suleyman Hilmi; Gonulalan, Gulsum; Ozturk, Mine; Kaya, Ahmet; Gonen, Mustafa Sait; Cakir, Mehtap[Abstract Not Availabe]Öğe Effects of diabetic education on metabolic parameters in type 2 diabetic patients using insulin(Elsevier Ireland Ltd, 2016) Kaya, Ahmet; Kulaksizoglu, Mustafa; Ozdamar, Fatma; Caglayan, Melek[Abstract Not Availabe]Öğe Hyperosmolar Nonketotic State Associated with Quetiapine(Galenos Yayincilik, 2014) Kaya, Ahmet; Turan, Elif; Ozlurk, Mine; Savut, Bulent; Kulaksizoglu, Mustafa; Gonulalan, GulsumA 67-year-old man was admitted to our hospital because of decreased oral intake and confusion. He had a 2-year history of diabetes mellitus and he had a good glycaemic control with oral antidiabetic drugs (latest HbA1C: 7.2%). Quetiapine was initiated 15 days ago in a psychiatric clinic because of depression. The patient was taken to the intensive care unit with the diagnosis of hyperosmolar nonketotic state and acute renal failure. All the medications were discontinued; intravenous hydration and insulin infusion were started. The relationship between secondgeneration antipsychotics (SGAs) and hyperglycemia is a topic of interest and insulin resistance is commonly accepted as the mechanism for hyperglycemia. Patients receiving SGAs should be followed more closely for metabolic disorders.Öğe İdiopatik Hipoparatiroidizme Bağlı 3 Fahr Hastalığı Vakası(2016) Turan, Elif; Gönen, Sait; Gönülalan, Gülsüm; Kulaksızoğlu, Mustafa; Kaya, AhmetBazal ganglionlarda bilateral kalsifikasyona bağlı nörolojik belirtiler Fahr hastalığı olarak bilinmektedir. Fahr hastalığının etiyolojisinde; idiopatik, konjenital, kalsiyum bozuklukları; ağırlıklı olarak hipoparatiroidiler, infeksiyonlar yer almaktadır. Bizim yazımızda hipoparatiroidiye bağlı bazal ganglionlarda bilateral kalsifikasyon ve ekstrapiramidal semptomları olan üç vakadan bahsedilecekÖğe An international survey on hypoglycemia among insulin-treated type I and type II diabetes patients: Turkey cohort of the non-interventional IO HAT study(Bmc, 2018) Emral, Rifat; Tetiker, Tamer; Sahin, Ibrahim; Sari, Ramazan; Kaya, Ahmet; Yetkin, Ilhan; Cil, Sefika UsluBackground: Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from Turkey cohort are presented here. Methods: A non-interventional study to determine the hypoglycemia incidence, retrospectively and prospectively, in Turkish T1DM and T2DM patients using a 2-part self-assessment questionnaire. Results: Overall, 2348 patients were enrolled in the Turkey cohort (T1DM = 306 patients, T2DM = 2042 patients). In T1DM patients, 96.8% patients reported hypoglycemic events (Incidence rate [IR]: 68.6 events per patient-year [ppy]), prospectively, while 74.0% patients reported hypoglycemic events (IR: 51.7 events ppy), retrospectively. In T2DM patients, 95.9% patients (IR: 28.3 events ppy) reported hypoglycemic events, prospectively, while 53.6% patients (IR: 23.0 events ppy) reported hypoglycemic events, retrospectively. Nearly all patients reported hypoglycemia during the prospective period. Conclusions: This is a first patient-reported dataset on hypoglycemia in Turkish, insulin-treated diabetes patients. A high incidence of patient-reported hypoglycemia confirms that hypoglycemia remains under-estimated. Hypoglycemia increased healthcare utilization impacting patients' quality of life. Hypoglycemia remains a common side effect with insulin-treatment and strategies to optimize therapy and reduce hypoglycemia occurrence in diabetes patients are required.Öğe Miscible Two Diseases in Old Age: Hypopituitarism and Pseudogout(Modestum Ltd, 2016) Gulyer, Huseyin; Savut, Bulent; Sahin, Muhammed; Gungor, Tayfun; Kucuk, Adem; Kulaksizoglu, Mustafa; Kaya, AhmetCalcium pyrophosphate dihydrate deposition disease is a disease characterized by collecting of crystals in hyaline cartilage, fibrocartilage and soft tissues, related to many endocrine and metabolic conditions, and seen more commonly in old age. Hypopituitarism may occur in old age with fatigue, decrease in libido, weight loss and musculoskeletal symptoms as a major cause of the overall condition impairment. As one gets older, the signs of these two diseases may progress even without any significant disease. The natural process which comes with old age, and pseudogout and hypopituitarism can mask one to another clinically and the symptoms of three situation may be overlapping. This can lead to difficulty and delay in diagnosis. Our case was an elderly female patient diagnosed with hypopituitarism and pseudogout.Öğe Miscible Two Diseases in Old Age: Hypopituitarism and Pseudogout(Modestum Ltd, 2016) Gulyer, Huseyin; Savut, Bulent; Sahin, Muhammed; Gungor, Tayfun; Kucuk, Adem; Kulaksizoglu, Mustafa; Kaya, AhmetCalcium pyrophosphate dihydrate deposition disease is a disease characterized by collecting of crystals in hyaline cartilage, fibrocartilage and soft tissues, related to many endocrine and metabolic conditions, and seen more commonly in old age. Hypopituitarism may occur in old age with fatigue, decrease in libido, weight loss and musculoskeletal symptoms as a major cause of the overall condition impairment. As one gets older, the signs of these two diseases may progress even without any significant disease. The natural process which comes with old age, and pseudogout and hypopituitarism can mask one to another clinically and the symptoms of three situation may be overlapping. This can lead to difficulty and delay in diagnosis. Our case was an elderly female patient diagnosed with hypopituitarism and pseudogout.Öğe Neutropenia Due to Very Long Time Propylthiouracil Usage in Toxic Multinodular Goiter(2016) Turan, Elif; Kaya, Ahmet; Mustafa, Kulaksızoğlu; Kandemir, Bahar; Erayman, İbrahimTirotoksikoz çeşitli yollarla hemtopoezi etkiler ve tionamidlerle birlikte miyelosupresyona neden olabilir. Toksik multinodüer guatra bağlı 20 yıl gibi uzun bir süre propiltiourasil kullanan ve febril nötropeni nedeniyle hastaneye yatışı yapılan hipertirodili bir hasta sunduk. Total tiroidektomi olduktan sonra hasta ötiroid iken nötropenisi düzeldi. Postoperatif patoloji ise mikropapiller tiroid karsinomu olarak değerlendirildi.Öğe The Prevalence of Insulin Resistance in the Turkish Population: A Study Conducted with 3331 Participants(Kare Publ, 2017) Kaya, Ahmet; Turan, Elif; Uyar, Mehmet; Bayram, Fahri; Turan, YasarObjectives: The aim of this study was to apply the homeostasis model assessment of insulin resistance (HOMA-IR) and examine the relationships between age, sex, and body mass index (BMI) and the prevalence of diabetes mellitus (DM) and insulin resistance (IR) in the Turkish population of different regions of the country. Methods: This was a cross-sectional, observational study designed in the framework of a multicenter study to analyze the Turkish prevalence of insulin resistance. The study sample consisted of volunteers from the 7 different regions of Turkey. Weight, height, and waist circumference were measured. BMI, blood pressure, fasting blood glucose, and fasting blood insulin levels were calculated. IR was determined using the HOMA-IR. Results: The prevalence of DM, impaired fasting glucose, and IR was 11.1%, 21.3%, and 26.2%, respectively, in all 7 regions of Turkey. IR was detected in 28.9% of women and 25.1% of men.The difference between men and women was significant (p=0.04). The prevalence of IR in postmenopausal women (30.8%) was higher than premenopausal women (25.1%) (p<0.04). A comparison of age groups revealed that the prevalence of IR among those aged 50 to 59 (33.8%; p<0.001) was higher than in the other age groups. IR was also more prevalent in those with a BMI >25 kg/m2, those with hypertension, and those living in city centers (p<0.05). Conclusion:The high prevalence of IR and DM in Turkey is an important public health problem. This study provides a large-sample representative study of the Turkish population. The prevalence of IR was highly correlated with central obesity, hypertension, and a more sedentary lifestyle, such as is often seen in city centers. There is an urgent need to institute more aggressive, nationwide public health measures and screening programs regarding obesity.Öğe The Prevalence of Insulin Resistance in the Turkish Population: A Study Conducted with 3331 Participants(Kare Publ, 2017) Kaya, Ahmet; Turan, Elif; Uyar, Mehmet; Bayram, Fahri; Turan, YasarObjectives: The aim of this study was to apply the homeostasis model assessment of insulin resistance (HOMA-IR) and examine the relationships between age, sex, and body mass index (BMI) and the prevalence of diabetes mellitus (DM) and insulin resistance (IR) in the Turkish population of different regions of the country. Methods: This was a cross-sectional, observational study designed in the framework of a multicenter study to analyze the Turkish prevalence of insulin resistance. The study sample consisted of volunteers from the 7 different regions of Turkey. Weight, height, and waist circumference were measured. BMI, blood pressure, fasting blood glucose, and fasting blood insulin levels were calculated. IR was determined using the HOMA-IR. Results: The prevalence of DM, impaired fasting glucose, and IR was 11.1%, 21.3%, and 26.2%, respectively, in all 7 regions of Turkey. IR was detected in 28.9% of women and 25.1% of men.The difference between men and women was significant (p=0.04). The prevalence of IR in postmenopausal women (30.8%) was higher than premenopausal women (25.1%) (p<0.04). A comparison of age groups revealed that the prevalence of IR among those aged 50 to 59 (33.8%; p<0.001) was higher than in the other age groups. IR was also more prevalent in those with a BMI >25 kg/m2, those with hypertension, and those living in city centers (p<0.05). Conclusion:The high prevalence of IR and DM in Turkey is an important public health problem. This study provides a large-sample representative study of the Turkish population. The prevalence of IR was highly correlated with central obesity, hypertension, and a more sedentary lifestyle, such as is often seen in city centers. There is an urgent need to institute more aggressive, nationwide public health measures and screening programs regarding obesity.Öğe A Rare Varieties of Diabetic Autonomic Neuropathy: Carotid Sinus Hypersensitivity, Case Report(2016) Kaya, Ahmet; Turan, Elif; Turan, Yaşar; Karanfil, Mustafa; Kulaksızoğlu, Mustafa; Güney, FigenCarotid sinus hypersensitivity is a common cause of fainting and falls in older adults and can be diagnosed by carotid sinus massage. We have presented a 67-year-old diabetic male patient who was admitted to our clinic because of hyperglycemia. In thyroid examination, clouding of consciousness occurred with unilateral palpation. Documented 4,8 seconds and undocumented 7 seconds of asystole were detected during the carotid sinus massage. An implantable cardioverter defibrillator was implanted in our patient. Carotid sinus hypersensitivity should be kept in mind in the examination of diabetic patients.Öğe Ratio of insulin cessation in patients with new onset insulin usage(Elsevier Ireland Ltd, 2016) Kulaksizoglu, Mustafa; Kaya, Ahmet; Ozdamar, Fatma[Abstract Not Availabe]Öğe Serum Selenium Levels in Euthyroid Nodular Thyroid Diseases(Humana Press Inc, 2016) Sakiz, Davut; Kaya, Ahmet; Kulaksizoglu, MustafaThe thyroid gland is susceptible to nodulation. The mechanism responsible for the growth of only some follicular cells, which results in nodule formation, is not yet clear. Selenium deficiency may be a risk factor in the development of thyroid nodules. The aim of this study was to investigate the relationship between selenium levels in patients with euthyroid nodular thyroid disease. Seventy patients with a solitary euthyroid thyroid nodule, 70 patients with more than one euthyroid nodule, and 60 healthy patients without thyroid nodules were included in the study. Venous serum samples were stored at -80A degrees C and analyzed the same day using spectrometry. The selenium levels of patients with multiple thyroid nodules, solitary nodules, and patients without nodules were 57.3 +/- 14.8 mu g/L; 58.8 +/- 15.1 mu g/L; and 57.6 +/- 13.3 mu g/L, respectively. The mean serum selenium level of all patients included in the study was 57.9 +/- 14.4 mu g/L. Although serum selenium levels were slightly higher in men, a statistically significant difference was not observed. In our study, a significant relationship between serum selenium levels and nodular thyroid disease was not seen. Our study was undertaken in an iodine sufficient region. Mean serum selenium levels were lower compared with many other studies, which may be associated with the low selenium content of the soil. Nodular thyroid disease shows multifactorial features. When our study is considered together with previous studies, serum selenium levels may considered to be effective on structural thyroid diseases if combined with additional factors such as severe iodine deficiency. Further studies are required to assess the role of selenium in thyroid nodule formation.Öğe Vitamin D Seasonal Variation in the Elderly in Residantial Care in Turkey(Kare Publ, 2018) Kaya, Ahmet; Turan, ElifObjectives: Many factors influence the intensity and duration of ultraviolet exposure, including geographic location, seasons, dietary intake, atmospheric conditions, and daily sunlight exposure. Our objective was to characterize the effect of diet and the seasonal variation of hypovitaminosis D in housebound elderly people in Konya Nursing Home (NH). Methods: In total, 41 old-aged participants (22 males, 19 females) who lived in Konya NH were included in the present study. Serum vitamin D3 (VD3) levels were measured and compared in the winter and summer for each group. The results were evaluated between each other and with 20 old-aged participants (10 women, 10 men) who had similar demographic conditions, were healthy, and living outside the NH. Results: The mean ages of the NH and control groups (CGs) were 74.75 +/- 3.90 (65-93) and 73.72 +/- 2.90 (68-83), respectively. The mean VD3 levels were 20.36 +/- 6.54 ng/mL in summer and 19.29 +/- 6.00 ng/mL in winter for men in the NH group. The mean VD3 levels were 19.58 +/- 6.93 ng/mL in summer and 18.29 +/- 4.69 ng/mL in winter for women in the NH group. The mean VD3 levels were 24.79 +/- 6.59 ng/mL in summer and 20.94 +/- 5.29 ng/mL in winter for men in the CG. For women in the CG, the mean levels were 25.30 +/- 6.77 ng/mL in summer and 20.73 +/- 6.50 ng/mL in winter. There were no differences in the mean levels between the NH group and CG in the summer and winter periods. Conclusion: VD is not required only for bone development and growth of children, it is also required bone strength in adults and prevent osteoporosis and fracture risk in the elderly. All of the seasons VD deficiency was found in older aged people in housebound and living outside. We must fortify the dietary products with VD and increase sunlight exposure in older aged people.Öğe Vitamin D Seasonal Variation in the Elderly in Residantial Care in Turkey(Kare Publ, 2018) Kaya, Ahmet; Turan, ElifObjectives: Many factors influence the intensity and duration of ultraviolet exposure, including geographic location, seasons, dietary intake, atmospheric conditions, and daily sunlight exposure. Our objective was to characterize the effect of diet and the seasonal variation of hypovitaminosis D in housebound elderly people in Konya Nursing Home (NH). Methods: In total, 41 old-aged participants (22 males, 19 females) who lived in Konya NH were included in the present study. Serum vitamin D3 (VD3) levels were measured and compared in the winter and summer for each group. The results were evaluated between each other and with 20 old-aged participants (10 women, 10 men) who had similar demographic conditions, were healthy, and living outside the NH. Results: The mean ages of the NH and control groups (CGs) were 74.75 +/- 3.90 (65-93) and 73.72 +/- 2.90 (68-83), respectively. The mean VD3 levels were 20.36 +/- 6.54 ng/mL in summer and 19.29 +/- 6.00 ng/mL in winter for men in the NH group. The mean VD3 levels were 19.58 +/- 6.93 ng/mL in summer and 18.29 +/- 4.69 ng/mL in winter for women in the NH group. The mean VD3 levels were 24.79 +/- 6.59 ng/mL in summer and 20.94 +/- 5.29 ng/mL in winter for men in the CG. For women in the CG, the mean levels were 25.30 +/- 6.77 ng/mL in summer and 20.73 +/- 6.50 ng/mL in winter. There were no differences in the mean levels between the NH group and CG in the summer and winter periods. Conclusion: VD is not required only for bone development and growth of children, it is also required bone strength in adults and prevent osteoporosis and fracture risk in the elderly. All of the seasons VD deficiency was found in older aged people in housebound and living outside. We must fortify the dietary products with VD and increase sunlight exposure in older aged people.
