Neutropenia Due to Very Long Time Propylthiouracil Usage in Toxic Multinodular Goiter
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Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Tirotoksikoz çeşitli yollarla hemtopoezi etkiler ve tionamidlerle birlikte miyelosupresyona neden olabilir. Toksik multinodüer guatra bağlı 20 yıl gibi uzun bir süre propiltiourasil kullanan ve febril nötropeni nedeniyle hastaneye yatışı yapılan hipertirodili bir hasta sunduk. Total tiroidektomi olduktan sonra hasta ötiroid iken nötropenisi düzeldi. Postoperatif patoloji ise mikropapiller tiroid karsinomu olarak değerlendirildi.
Thyrotoxicosis affects hematopoiesis in several ways and thioamides may cause myelosuppression. We report a case of febrile neutropenia in a patient with hyperthyroidism who was using propylthiouracil for nearly 20 years for the treatment of toxic multinodular goitre. After surgery, the patient was euthyroid and neutropenia resolved. Postoperative pathology was evaluated as micropapillary thyroid carcinoma.
Thyrotoxicosis affects hematopoiesis in several ways and thioamides may cause myelosuppression. We report a case of febrile neutropenia in a patient with hyperthyroidism who was using propylthiouracil for nearly 20 years for the treatment of toxic multinodular goitre. After surgery, the patient was euthyroid and neutropenia resolved. Postoperative pathology was evaluated as micropapillary thyroid carcinoma.
Açıklama
Anahtar Kelimeler
Thyrotoxicosis, Neutropenia, Propylthiouracil, Tirotoksikoz, Nötropeni, Propiltiourasil
Kaynak
Turkish Journal of Endocrinology and Metabolism
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
20
Sayı
1
Künye
Kulaksızoğlu, M., Erayman, İ., Kandemir, B., Turan, E. (2016). Neutropenia Due to Very Long Time Propylthiouracil Usage in Toxic Multinodular Goiter. Turkish Journal of Endocrinology and Metabolism, 20, 1, 16-18.
