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    According to the normal weight, overweight and obese comparison of bioelectric impedance analysis method with the other methods
    (2015) Çakmakçı, Evrim; Arslan, Fatma; Vatansev, Hüsamettin; Ayrancı, Meryem
    Women are faced with the problem of obesity because of over-nutrition, still life and birth weight. To Assess overweight and obesity are used with Body mass index (BMI), waist circumference, waist/hip ratio and skinfold thickness measurement method and Bioelectrical impedance analysis method. The purpose of this study was to compare of the methods used to assess body composition in normal weight, overweight and obese in adults women. In this study participated adult women that the mean age of normal weight 25.70 ± 7.85 (N 17), overweight 32.47 ± 8.22 (N 36), obese 38.12 ± 8.95 (N 40) and total N 93. Subjects body composition were evaluated with Body mass index, waist circumference, waist/hip ratio and skinfold thickness measurements and measured using bioelectric impedance analysis. For statically analysis, One Way Anova and Tukey tests were performed. Significance level was accepted as 0.05 for all tests. According to the results of anthropometric measurements was found BMI, waist circumference, and bioelectrical impedance analysis method for all the groups differ (p >0.05), waist / hip ratio values were found to be different between normal weight and obese groups (p >0.05) that participated in the research. Body mass index and bioelectric impedance are important methods to detect of obesity, and the waist circumference be used together these methods to determine the abdominal obesity may be more useful.
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    Öğe
    Karotid endarterektomi geçiren hastalarda kontrolsüz diyabetin statin kullanan ve kullanmayan hastalarda LDL seviyelerine etkisi
    (2016) Öç, Mehmet; Duman, İpek; Vatansev, Hüsamettin; Şimşek, Murat; Arun, Oğuzhan; Öç, Bahar
    Amaç: Çalışmanın amacı Karotid endarterektomi geçiren hastalarda kontrolsüz diyabetes mellitusun (DM) uzun süreli statin kullanan ve kullanmayan hastalarda Düşük Yoğunluklu Lipoprotein (LDL) seviyelerine etkisini araştırmaktı.Gereç ve yöntem: Ateroskleroz nedeniyle karotid endarterektomi geçiren 40 hastanın ameliyat öncesi LDL seviyeleri retrospektif olarak analiz edildi. Tüm hastalar en az 1 yıldır statin kullanıyordu. HbA1C seviyelerinin % 6,4'den fazla olması kontrolsüz DM kriteri kabul edildi (D). Diğer hastalar diyabet olmayan gruplara alındı (D-). Grup 1: D statin kullanan (n9), grup 2: D- statin kullanan (n10), grup 3: D statin kullanmayan (n8), grup 4: D- statin kullanmayan (n13) hastalardan oluştu. İstatistiksel değerlendirme için Kruskal-Wallis ve Mann-Whitney testleri kullanıldı. p0,05 anlamlı kabul edildi.Bulgular: Demografik veriler benzerdi. Grup 1, 2, 3 ve 4 için LDL seviyeleri sırasıyla 125,08,7 mg/dl, 95,07,0 mg/dl, 133,510,0 mg/dl, 114,010,2 mg/dl olarak bulundu. ). Statin kullanan ve kullanmayan kontrolsüz diyabet hastalarının LDL seviyeleri diğer gruplardan anlamlı derecede yüksekti (p0,05). Statin kullanan diyabetik hastaların LDL seviyeleri de statin kullanan normal hastalardan daha yüksekti (p0,05). Kontrolsüz diyabet olan hastaların LDL seviyeleri statin kullanan ve kullanmayan gruplarda benzerdi (p0,05). Diyabet olmayan hastaların LDL seviyeleri benzer bulundu (p0,05).Sonuç: Bu çalışma, kontrolsüz diyabeti olan ateroskleroz hastalarının LDL seviyelerinin, statin kullansınlar ya da kullanmasınlar diyabet olmayan ateroskleroz hastalarından daha yüksek olduğunu göstermiştir. İleri çalışmaların kanıtlanmış aterosklerozu olan hasta gruplarında çok merkezli ve yüksek vaka sayılı olarak yapılmasının uygun olacağı görüşündeyiz.
  • Küçük Resim
    Öğe
    Preventing oxygen free radical damage by proanthocyanidin in obstructive jaundice
    (2017) Savdan, Mervan; Çakır, Murat; Vatansev, Hüsamettin; Küçükkartallar, Tevfik; Tekin, Ahmet; Tavlı, Şakir
    Objective: Tissue damage and endotoxemia in obstructive jaundice are attributed to the increase in oxygen freeradicals. We aimed at evaluating the possible protective effect of grape seed proanthocyanidin extract (GSPE), whichis a potent exogenous free-radical scavenger and antioxidant.Material and Methods: The study was performed at the Necmettin Erbakan University Meram School of MedicineResearch and Application Center for Experimental Medicine Laboratory with ethical approval. 30 Wistar-Albino ratswere used and were divided into 3 groups. The common bile duct was identified and only dissected in the first group(sham). Following dissection of the common bile duct it was ligated with 4/0 silk just above the pancreas in thesecond group (control). After ligation of the common bile duct, 100mg/kg/day GSPE was administered via orogastriclavage for 10 days in the third group.Results: Biochemical values revealed a statistically significant difference between Group I and the others. There wasno difference between Group II and III regarding biochemical values. There was a statistically significant difference,however, between Group II and III with regards to nitric oxide levels. There was a statistically significant differencebetween Group I and the other groups concerning hepatic and pulmonary tissue damage on histopathologic evaluation. There was no difference among the groups with regards to renal tubular damage.Conclusion: Proanthocyanidin is an effective natural antioxidant in decreasing the level of tissue damage causedby oxygen free-radicals.