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Öğe Akut Bronşiyolitte İzole Edilen Viral Patojenlerin ve Uygulanan Tedavi Yöntemlerinin Hastalığın Seyrine Etkisi(2017) Akın, Fatih; Yazar, Abdullah; Arslan, ŞükrüGiriş ve Amaç: Akut bronşiyolit süt çocukluğunda ve 2 yaşından küçük çocuklarda, genellikle viral etkenlere bağlı gelişen ve hastaneye yatışın majör sebeplerinden olan bir alt solunum yolu enfeksiyonudur. Çalışmamızın amacı akut bronşiolit nedeniyle hastanede yatan çocuklarda izole edilen laboratuvar bulguları ve uygulanan tedavi yöntemlerinin hastaların yatış sürelerine etkisini araştırmaktır.Yöntem ve Gereçler: Bu amaçla Konya Eğitim ve Araştırma Hastanesi Çocuk Kliniğinde Aralık 2013 - Mayıs 2014 tarihleri arasında bronşiyolit tanısıyla yatarak takip edilen 95 hastanın dosyaları retrospektif olarak incelendi.Bulgular: En fazla izole edilen viral patojenler respiratuvar sinsityal virüs (%21.8) ve rinovirüs idi (%21.8). Sadece rinovirüs üreyen grupla üreme olmayan grup arasında yatış süreleri açısından anlamlı bir fark bulunamazken, sadece RSV-A üreyen ve RSV-ARinovirüs birlikte üreyen grupta hastanede yatış süreleri anlamlı derecede uzun bulundu. İnhale bronkodilatatör, ipratropium bromid, hipertonik salin tedavisi uygulanan ve uygulanmayan hasta grupları arasında yatış süreleri açısından anlamlı fark saptanmazken, inhale streoid alan olguların yatış süresi almayanlara oranla daha uzun bulundu. İmmunglobulin E (Ig E) düzeyi yüksek ölçülen hastaların ortalama yatış süreleri, normal olanlara göre anlamlı olarak uzundu. Anne sütü alan ve almayan gruplar arasında ve sigara ile temas öyküsü olan ve olmayan gruplar arasında yatış süreleri açısından anlamlı fark saptanmadı.Tartışma ve Sonuç: Sonuç olarak, RSV ve rinovirüs hala akut bronşiyolitin majör sebepleridir. İnhale steroid tedavisi almak, yüksek Ig E düzeyi ve bronşiolit sebebinin RSV olması hastanede yatış süresini uzatmaktadır.Öğe Clinical and Laboratory Evaluations of Patients Diagnosed as Having Multisystem Inflammatory Syndrome Associated with Coronavirus Disease 2019 in Children: A Single Center Experience from Konya(Georg Thieme Verlag Kg, 2023) Genceli, Mustafa; Akcan, Ozge Metin; Erdogan, Kubra Nur; Kilic, Ahmet Osman; Yazar, Abdullah; Akin, Fatih; Gunes, MuhammedObjective Multisystem inflammatory syndrome in children (MIS-C), characterized by fever, inflammation, and multiorgan dysfunction, was newly defined after severe acute respiratory syndrome coronavirus 2 infection. The clinical spectrum of MIS-C can be classified as mild, moderate, and severe. We aimed to evaluate demographics, clinical presentations, laboratory findings, and treatment modalities of patients with MIS-C according to clinical severity.Methods We performed a retrospective study of patients who were diagnosed as having MIS-C between September 2020 and October 2021 in the Necmettin Erbakan University Meram Faculty of Medicine, Turkey.Results A total of 48 patients (24 females and 24 males) with a median age at diagnosis of 10.3 years (range: 42 months-17 years) were enrolled, the most common clinical severity of MIS-C was moderate. The common presentations of patients were fever (97%), nonpurulent conjunctivitis (89.6%), rashes (81.3%), fatigue (81.3%), strawberry tongue (79.2%), and myalgia (68.8%). The most common laboratory findings were lymphopenia (81.2%), thrombocytopenia (54.1%), elevated D-dimer levels (89.5%), C-reactive protein (CRP; 100%), procalcitonin (97%), erythrocyte sedimentation rate (87.5%), ferritin (95.8%), interleukin 6 (IL-6) (86.1%), and probrain natriuretic peptide (pro-BNP) (97%). High levels of CRP, procalcitonin, pro-BNP, and urea were associated with the severity of MIS-C ( p < 0.05). Fifteen of the patients were found to have pulmonary involvement. Ascites were the most common finding on abdominal ultrasonography (11 patients) and were not seen in a mild form of the disease. During the study period, two patients died.Conclusion It is important to make patient-based decisions and apply a stepwise approach in treating patients with MIS-C due to the increased risk of complications and mortality.Öğe Çocuk Acil Kliniğine Başvuran Adli Vakaların Değerlendirilmesi(2017) Yazar, Abdullah; Akın, Fatih; Türe, Esra; Odabaş, DursunGiriş: Çocukluk çağında meydana gelen adli olaylar tüm dünyada önlenebilir sağlık sorunlarının başında yer almaktadır. Bu çalışmada çocuk acil kliniğine başvuran, majör travma dışı adli vaka olarak değerlendirilen hastaların klinik ve demografik özelliklerinin ve tedavi yaklaşımlarının değerlendirilmesi amaçlanmıştır. Yöntemler: Çocuk acil tıp kliniğimize Eylül 2015-Eylül 2016 tarihleri arasında başvuran 18 yaş altı 39756 hastadan, adli vaka olarak kabul edilen 683 hastanın dosyaları retrospektif olarak incelendi. Sonuç: Tüm dünyada olduğu gibi ülkemizde de kazalar ve intoksikasyon vakaları, önlenebilir ölüm nedenlerinin başında gelmektedir. Bu tür olayların azaltılabilmesi için çocukların yaşadığı çevrelerde ve evde güvenlik için gerekli düzenlemeler yapılmalı, güvenliği sağlamak için gerektiğinde uygun güvenlik araçları kullanılmalıdır. Ayrıca eğitimciler ve sağlık profesyonelleri tarafından çocuklara ve ebeveynlere yaralanma korunma programları çerçevesinde düzenli eğitimler verilmelidir.Öğe Çocuk Hastada Nadir Bir Göğüs Ağrısı Nedeni: Spontan Pnömomediastinum(2018) Yazar, Abdullah; Türe, Esra; Akın, Fatih; Pekcan, Sevgi; Odabaş, DursunSpontan pnömomediastinum (Hamman’s sendromu)nadir görülen, kendini sınırlayan genellikle gençerişkin erkeklerde görülen bir hastalıktır. Pulmoner interstisyumdaalveolar rüptüre sekonder intratorasik basınçartışı sonucu, havanın hilum ve mediastene doğruilerlemesi sonucu ortaya çıkar. Olgular çoğunlukla göğüsağrısı, boyun ağrısı, sırta yayılan ağrı, ses kısıklığı,yutma güçlüğü ve öksürük şikayetleri ile başvururlar. Buyazıda çocuk acil kliniğine göğüs ağrısı ile başvurup,değerlendirme sonrası spontan pnömomediastinum(SPM) saptanan olgumuz, göğüs ağrısının ayırıcıtanısında SPM’ye dikkat çekmek amacıyla sunulmuştur.Öğe Determining the Infectious Pathogens and Their Resistance to Antibiotics in a Pediatric Intensive Care Unit(Georg Thieme Verlag Kg, 2018) Akin, Fatih; Yazar, Abdullah; Dogan, MetinIntroduction Nosocomial infections are one of the main causes of morbidity and mortality. It is important to know the common infectious pathogens and their resistance profiles in intensive care units (ICUs) to determine appropriate treatment protocols. The aimof this study was to determine the epidemiological profile of microorganisms isolated in a pediatric ICU (PICU) and to determine antibiotic resistance in isolated strains. Materials and Methods This retrospective study was performed at the Meram Medical Faculty Hospital, Necmettin Erbakan University, Konya, Turkey. A total of 1,502 bacteria that were isolated from various specimens from children who were hospitalized in PICUs between January 2014 and December 2015 were included in this study to determine the isolated bacteria diversity and susceptibility to various antibiotics. Results Staphylococcus spp. was the most frequently isolated microorganism followed by Escherichia coli and Klebsiella spp., respectively. The sites where pathogens were isolated were as follows: 616 blood, (41%), 445 urine (29.6%), 60 sputum (4%), 44 cerebrospinal fluid (2.9%), 25 wound swab (1.6%), 20 tracheal aspirate (1.3%), and 26 others (1.7%). The carbapenem resistance rate was 40.8% among Pseudomonas aeruginosa isolates. Among 60 Acinetobacter baumannii isolates tested, 62% were resistant to carbapenems. Sensitivity rates of A. baumannii isolates to tigecycline and colistin were as high as 98 and 96%, respectively. Meropenem and colistin resistance rates to Klebsiella spp. were 16.2 and 15%, respectively. Conclusion In conclusion, it is essential to identify the infectious pathogens and their resistance to antibiotics especially in ICUs where infections with multidrug-resistant bacteria are frequent. Studies on this issue should be performed at appropriate time intervals.Öğe Early kidney injury in immunoglobulin A vasculitis: Role of renal biomarkers(Wiley, 2021) Ture, Esra; Yazar, Abdullah; Akin, Fatih; Topcu, Cemile; Aydin, Arif; Balasar, Mehmet; Atas, BulentBackground We aimed to determine whether urine kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) can be used as early noninvasive biomarkers of kidney injury in immunoglobulin A vasculitis. Methods Patients who were diagnosed with immunoglobulin A vasculitis were included in the study. Urine samples were collected for determination of urine KIM-1 and NGAL levels. The control group consisted of age-matched healthy children. Results Sixty-one patients who were diagnosed with immunoglobulin A vasculitis were included in the study; 37.7% of these patients were determined to have renal involvement. Median KIM-1 was found to be significantly higher in the patient group (69.59 pg/mL) than the control group (40.84 pg/mL) (P = 0.001). Median NGAL was determined to be statistically significantly higher in the patient group (59.87 ng/mL) compared with the control group (44.87 ng/mL) (P = 0.013). In 23.6% of the patients without renal involvement at admission renal involvement developed within the following 6 months. When median KIM-1 and NGAL at admission of these patients were compared with the control group, they were determined to be statistically significantly higher (P = 0.001, P = 0.003). Conclusions The fact that our patients with late-term nephropathy had no hematuria and / or proteinuria and that KIM-1 and NGAL levels were determined to be high indicates that these biomarkers might be potentially reliable, noninvasive and early determinants of kidney injury.Öğe The effect of attention deficit/hyperactivity disorder and other psychiatric disorders on the treatment of pediatric diabetes mellitus(Wiley-Hindawi, 2019) Yazar, Abdullah; Akin, Fatih; Akca, Omer F.; Eklioglu, Beray S.; Ture, Esra; Coskun, Fatma; Atabek, Mehmet E.Objective Psychiatric diagnoses of patients with type 1 diabetes mellitus (T1DM), the severity of attention deficit/hyperactivity disorder (ADHD) symptoms of the patients and their primary caregivers, and the effects of these factors on treatment were investigated. Methods Sixty-one patients with T1DM were included in the study along with their parents. Psychiatric diagnoses of the patients were determined using a semistructured psychiatric interview, and their depression and ADHD symptom severities were evaluated with self-report scales. The ADHD symptom severities of the parents were evaluated using self-report scales. The relationships among the psychiatric symptoms and the hemoglobin A1c (HbA1c), fasting blood glucose (FBG), and postprandial blood glucose (PBG) levels of the patients were investigated. Results HbA1c levels were found to correlate with the hyperactivity levels of children and the number of diagnoses they had. FBG and PBG values of patients diagnosed with ADHD were found to be higher than in those who did not have ADHD. HbA1c, FBG, and PBG values of the patients who had any disruptive behavior disorder were found to be higher than in those who did not. ADHD total scores, gender (being female), having diagnoses of ADHD or depression were found to be predictive of HbA1c levels according to the regression analyses. No relationship between the clinical findings of the children and their parents' ADHD levels was found. Conclusions The findings of this study implicate that children with T1DM should be evaluated in terms of ADHD which could have negative effects on the treatment.Öğe Goldenhar Sendromu Goldenhar Sendromu Astım - Kardiyolojik Hastalık Profillendirmesi ve Hava Kalitesi Değerlendirmesi(2017) Yazar, Abdullah; Akın, Fatih; Türe, EsraAmaç: Gastrointestinal sistem kanaması çocukluk çağında her yaşta karşımıza çıkabilen ve ağızdan anüse kadar her yerinde görülebilen önemli bir çocuk acil sorunudur. Bu çalışmada çocuk acil kliniğimize gastrointestinal kanama ile başvuran hastaların epidemiyolojik ve laboratuvar özelliklerini ve kanamanın etiyolojik nedenlerini araştırmayı amaçladık.. Yöntem: Çocuk Acil kliniğine Ocak 2016-Ocak 2017 tarihleri arasında başvuran, gastrointestinal kanama tanısı almış 18 yaş altı hastaların, kayıtları ve yatış dosyaları retrospektif olarak incelendi. Hastaların yaş, cinsiyet, geliş yakınmaları, kullandığı ilaçlar, laboratuvar bulguları, aldıkları tanılar, tedavi yöntemleri, endoskopi ve kolonoskopi bulguları incelendi. Bulgular: Çocuk acil kliniğine son bir yılda başvuran hastaların 47'si gastrointestinal kanama tanısı aldı. Bunların 24'ü (%51,1) üst, 23'ü (%48,9) alt gastrointestinal kanama idi. Hastaların %40,4'ünde (n: 19) hematemez, %14,9'unda (n: 7) melena ve %44,7'sinde (n:21) hematokezya tespit edildi. Melena ile başvuranların istatistiksel anlamlı olarak (p:0,02) en fazla 5 yaş altında (n:4, %57,1) olduğu görüldü. Hastaların 20'sinde (%42,6) ilaç kullanım hikayesi mevcuttu. İlaç kullanım hikayesi olan 20 hastanın 18'nin (%90) istatistiksel anlamlı olarak non-steroid anti-inflamatuar ilaç kullandığı tespit edildi. Helicobacter pylori pozitif tespit edilen 12 hastanın 6'sı (%50) istatistiksel anlamlı olarak gastrit tanısı aldı. Helicobacter pylori pozitif tespit edilen 12 hastanın 6'sının (%50) istatistiksel anlamlı olarak hematemez ile başvurduğu görüldü. Sonuç: Bu çalışmada gastrit ve peptik ülserin gastrointestinal kanamanın en sık nedenleri olduğu görüldü. Gastrointestinal kanamaları risk faktörlerine göre değerlendirildiği zamannon-steroid anti-inflamatuar kullanımı ve Helicobacter pylori enfeksiyonunun mukozal lezyonlar ile ilişkisi ortaya koyuldu. Bu nedenle hastaların çocuk acil kliniklerinde özenle değerlendirilip yakın izleme alınması aynı zamanda hasta yakınlarının akılcı ilaç kullanımı konusunda bilgilendirilmesi gerekmektedir.Öğe How Should We Measure Body Temperature in the Pediatric Emergency Department? Which One Is the Most Accurate?(Georg Thieme Verlag Kg, 2019) Ture, Esra; Yazar, AbdullahThe aim of this study is to evaluate temperature measurement methods in children. Body temperatures of 3 to 18 years old patients were measured with a tympanic infrared thermometer, a noncontact infrared skin thermometer and with a temporal artery thermometer. While the specificity of temporal artery and noncontact thermometers were good in determination of temperatures above 37.5 degrees C, their sensitivities were low. Positive predictive value and negative predictive value for both thermometers were sufficient. Both specificity and sensitivity of both thermometers were determined to be good at temperature values above >= 38 degrees C. It is thought that noncontact and temporal artery thermometers can be used for screening in pediatric emergency departments.Öğe Investigation of the Relation between Epithelial Barrier Function and Autism Symptom Severity in Children with Autism Spectrum Disorder(Springernature, 2022) Nalbant, Kevser; Erden, Semih; Yazar, Abdullah; Kilinc, IbrahimAutism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by limitations in mutual communication and social interaction as well as restricted, repetitive patterns of behaviors, interests, or activities. The possible role of biological abnormalities in the etiopathogenesis of this disorder arouses research interest in this area. This is a case-control study evaluating epithelial barrier function by comparing serum concentrations of occludin and zonulin in children with ASD (n = 60) and controls (n = 30). The Childhood Autism Rating Scale (CARS) was used to evaluate autism symptom levels in all children. Serum occludin and zonulin levels were analyzed using an enzyme-linked immunosorbent assay. Serum occludin was significantly lower in children with ASD than in control subjects. In children with ASD, a decrease in occludin level was significantly associated with the disorder symptom levels items mean score (CARS total scores). Our findings showed that children with ASD had alterations in epithelial barrier function compared to the control group. The investigation of the mechanism underlying the different levels of occludin between ASD and controls may be of importance in clarifying the etiopathogenesis of ASD, as well as its follow-up and treatment.Öğe Is Asymmetric Dimethylarginine a Useful Biomarker in Children With Carbon Monoxide Poisoning?(Lippincott Williams & Wilkins, 2019) Yazar, Abdullah; Akin, Fatih; Sert, Ahmet; Ture, Esra; Topcu, Cemile; Yorulmaz, Alaaddin; Ercan, FatihObjective Carbon monoxide poisoning (COP) is the leading cause of mortality and morbidity due to poisoning worldwide. Because children are affected more quick and severely from COP, they may require a longer treatment period, even if carboxyhemoglobin (CO-Hb) and/or lactate levels return to normal. Therefore, a new marker that predicts the duration of treatment and the final outcomes of COP is needed. Methods This case control study was conducted on 32 carbon monoxide-poisoned patients younger than 18 years who had been admitted to pediatric emergency department. The control group included age- and sex-matched 30 healthy children. Blood samples were obtained for analysis of arterial blood gases, CO-Hb percent, methemoglobine, lactate, and asymmetric dimethylarginine (ADMA). Results Asymmetric dimethylarginine levels were significantly increased (P < 0.05) in patients with COP on admission and after the treatment when compared with controls (1.36 [0.89-6.94], 1.69 [0.76-7.81], 1.21 [0.73-3.18] nmol/L, respectively). There was no positive correlation between CO-Hb and ADMA levels on admission and at 6 hours (P = 0.903, r = 0.218, P = 0.231, r = 0.022, respectively). Positive correlation was found between lactate and CO-Hb levels on admission (P = 0.018, r = 0.423). Conclusions This study showed that ADMA levels were still high after 6 hours of 100% oxygen therapy in children with COP, even CO-Hb and/or lactate levels return to normal range. On the basis of these results, we consider that ADMA may be a useful biomarker in patient with COP.Öğe Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio May Be Used as Predictors in Febrile Seizures(Georg Thieme Verlag Kg, 2018) Yazar, Abdullah; Akin, Fatih; Ture, Esra; Caksen, Huseyin; Odabas, DursunFebrile seizure (FS) is the most frequent seizure disorder in childhood, associated with rapid onset of high fever. Our study aims are (1) to determine if the levels of mean platelet volume (MPV) and neutrophil-to-lymphocyte ratio (NLR) are risk factors for FS and to (2) assess the usefulness of these markers as predictors to distinguish the subgroups of FS. This prospective study includes children with FS, acute febrile illness (AFI) without seizure, and control group. Complete blood count was performed on all participants. The following data were obtained: white blood cell count (WBC), platelet count, MPV, hemoglobin (Hb), absolute neutrophil count (ANC), absolute lymphocyte count (ALC), and NLR. MPV, WBC, ANC, and NLR were significantly increased in patients with AFI and FS compared with controls (p < 0.05). When patients with FS and AFI were compared, only WBC was increased significantly in patients with FS (p < 0.05). WBC, ANC, and NLR were significantly increased in patients with complex FS compared with simple (p < 0.05). Our findings showed that WBC, MPV, ANC, and NLR were higher in children with FS than in the control group. Additionally WBC, ANC, and NLR were found to be higher in children with CFS than in those with simple febrile seizure. Based on the study results, we suggest that only WBC may be used as predictors in children with FS.Öğe Nadir Bir Olgu: Eksantem Subitum Sonrası Ensefalit(2017) Akın, Fatih; Yazar, Abdullah; Türe, Esra; Odabaş, DursunHuman herpes virüs tip 6 (HHV-6) çocuklarda özellikle yaşamın ilk iki yılında görülen benign, ateşli bir hastalık olan exanthem subituma (ES) neden olur. ES ani başlayan yüksek ateş ve ateşin düşmesiyle birlikte döküntünün ortaya çıkmasıyla karakterize bir hastalıktır. ES hastalarında en sık görülen komplikasyonlar febril nöbet ve ensefalit gibi merkezi sinir sistemi (MSS) komplikasyonlarıdır. Bu yazıda çocuk acil kliniğimize döküntü, emmede azalma ve uykuya meyil şikayetleri ile gelen ve ES sonrası ensefalit tanısı konulan bir olgu sunulmuştur.Öğe Nadir Bir Olgu: Kabuki Make-Up Sendromu(2017) Türe, Esra; Yazar, Abdullah; Akın, Fatih; Zaimoğlu, Ayşe Gül; Odabaş, DursunKabuki make-up sendromu (KMS) multipl konjenital anomaliler ve mental retardasyonla seyreden, kalıtım şekli tam bilinmeyen ancak otozomal dominant bir mutasyonun sebep olduğu düşünülen nadir bir sendromdur. Bu yazıda, mental-motor retardasyon, geniş alın, yukarı doğru kavisli kaş kemeri, lateral 2/3'si dökük kaşı, çekik ve ayrık gözleri, alt göz kapak lateralinde dışa dönüklüğü, basık ve geniş burun kökü, gaga burnu, bilateral geniş ve düşük kulak sayvanları, seyrek ve kırılgan saçları, dar ve yüksek damağı, dismorfik dişleri, belirgin el parmak pulpaları, 5. parmak kısalığı ve karaciğer enzim yüksekliği saptanan 27 aylık bir kız çocuğu literatüre katkıda bulunmak amacıyla sunulmuştur.Öğe Outcomes of COVID-19 Infections in children: A single-center retrospective study(Wiley, 2022) Genceli, Mustafa; Akcan, Ozge Metin; Pekcan, Sevgi; Akin, Fatih; Ozdemir, Mehmet; Kilic, Ahmet Osman; Yazar, AbdullahThe COVID-19 pandemic is an important cause of morbidity and mortality, which has had a negative impact worldwide. Our aim was to describe clinical findings and outcomes of severe acute respiratory syndrome (SARS)-CoV-2 viral infection and COVID-19 cared for at a large pediatric tertiary care hospital during the first year of the pandemic. Patients aged 1 month to 18 years who were diagnosed as having COVID-19 between March 2020 and April 2021 were included. The files of patients diagnosed with COVID-19 were reviewed retrospectively. Results: Four hundred sixty seven children were included in the study. There were 34 (7.3%) patients under 1 year of age, 111 (23.8%) between 1 and 5 years, 98 (30.4%) between 5 and 10 years, 142 (30.4%) between 11 and 15 years, and 82 (17.6%) age over 15 years. Fever (88.2%), vomiting (32.4%), and diarrhea (29.4%) in patients aged under 1 year, sore throat (36.6%) in patients aged 11-15 years, and dysgeusia (11%), anosmia (14.6%), headache (18.3%), malaise (40.8%), myalgia (28%), and shortness of breath (17.1%) in those aged over 15 years were found to be significantly more common in comparison with the other age groups (p < 0.05). Thirty-five (7.5%) patients were asymptomatic, 365 (78.1%) had mild disease, 35 (7.5%) were moderate, 27 (5.8%) were severe, and five (1.07%) were critical. Leukocyte count, erythrocyte sedimentation rate, ferritin, and C-reactive protein values were significantly higher in hospitalized patients. Three patients died during the study period (0.64%). While SARS-CoV-2 infection may be asymptomatic and COVID-19 usually has a mild clinical course, some children have severe disease or mortality.Öğe Paediatric systemic lupus erythematosus: A single referral centre experience(Pakistan Medical Assoc, 2021) Atas, Bulent; Bulut, Mustafa; Sap, Fatih; Yazar, Abdullah; Akin, Fatih; Poyraz, Necdet; Tokgoz, HuseyinIn this study, the clinical and laboratory findings, management and follow-up of 32 children with paediatric systemic lupus erythematosus (pSLE) were evaluated to determine the prognostic factors in pSLE. Of the 32 patients, 25 (78.1%) were females. Age at onset of symptoms and diagnosis in the patients were 147.6 +/- 49 months and 154.3 +/- 48 months, respectively. The most common symptom on admission were joint problems, seen in 25 (78.1%) patients. Haematological alterations were seen in 25 (78.1%) cases during follow-up. Lupus nephritis was diagnosed in 10 (31.2%) patients. Malar rash was seen in a total of 12 (37.5%) patients during follow up, however it had been noted in five (15.6%) patients on admission. Antinuclear antibody and anti-dsDNA were positive in all patients and 31 (96.8%) patients, respectively. Decreased complement 3 and 4 levels were noted in 23 (71.8%) patients. Antiphospholipid antibody was studied in 27 patients and it was found to be positive in 13 (48.1%) patients. In conclusion, based on our findings, we would like to emphasize that pSLE has a large and remarkable clinical and laboratory findings.Öğe Plastic Bronchitis and Human Bocavirus: A Report of Three Cases(Georg Thieme Verlag Kg, 2023) Yilmaz, Asli Imran; Copur, Ahmet; Parlatan, Havva; Caglar, Hanife Tugce; Unal, Gokcen; Ercan, Fatih; Yazar, AbdullahThis study aims to investigate and analyze the clinical features of coexisting human bocavirus (HBoV) positivity and plastic bronchitis (PB). We present three cases with no known history of cardiac surgery who presented with cough, progressive dyspnea, and atelectasis. They tested positive for HBoV in a real-time polymerase chain reaction of both nasal lavage fluids. They were diagnosed with PB as a result of bronchoscopy and pathology. PB is a rare disease characterized by forming thick rigid casts in the tracheobronchial tree, which can progress to respiratory failure. While asthma or atopy-related type 1 PB was observed in one patient, two patients were diagnosed with PB, which was thought to have developed secondary to viral infections of unknown etiology. As far as we know, HBoV-associated PB cases are rare in the literature. Besides the commonly known infectious agents, we identified a relationship with HBoV in all the presented cases.Öğe A Rare Complication during Salmonella sp. Infection in a 4-Year-Old Child: Acute Pancreatitis(Georg Thieme Verlag Kg, 2021) Kilic, Ahmet O.; Akin, Fatih; Yazar, Abdullah; Cokbicer, Abdulkerim; Dogan, Metin; Energin, Vesile M.Objective We aimed to report a rare complication of acute pancreatitis which developed during Salmonella infection. Methods We report a 4-year-old girl with pancreatitis that occurred after salmonella gastroenteritis. Discussion Salmonella sp. infections cause serious mortality and morbidity worldwide. Salmonella transmission is mostly fecal oral from contaminated water and foods. Acute pancreatitis expresses the acute inflammatory process of the pancreas. Inflammation of the pancreas associated with bacterial, viral, and fungal agents can lead to acute pancreatitis. There are limited data regarding the frequency of infections leading to pancreatitis. Here, a pediatric case with pancreatitis that occurred after salmonella gastroenteritis is reported. Conclusion Acute pancreatitis due to S. sp. infection is very rare in children. Pancreatitis should be considered in patients with gastroenteritis with typical abdominal pain.Öğe Retrospective Evaluation of Return Visits to the Paediatric Emergency Department(Emergency Medicine Physicians Assoc Turkey, 2020) Ture, Esra; Yazar, AbdullahAim: This study aimed to establish regional data using the results obtained via determination of clinical and demographic characteristics of patients who revisited the paediatric emergency department of a university hospital within 5 days. Materials and Methods: Patients who revisited the paediatric emergency department within the first 5 days were included. Patient age and sex, complaints at admission, admission sessions and timeframes and whether the patients were admitted during or outside of working hours were recorded. Results: The emergency department was revisited by 654 (1.32%) patients. When patient distribution by age group was examined, 415 patients were found to be aged <5 years. When patient distribution based on working hours was examined, 302 patients were found to be admitted outside of working hours and on holidays, whereas 291 patients were usually admitted during the evenings. Conclusion: Clinicians informing parents at the first visit of the details about their child's disease, the disease course and when to revisit the hospital after discharge may be an effective way to not only prevent unnecessary return visits but also alleviate the anxiety of parents and reduce medical errors and negative patient outcomes.Öğe Romatizmal mitral yetmezlikli hastalarda sol ventrikül sistolik ve diyastolik fonksiyonlarının geleneksel ve doku doppler yöntemleri ile değerlendirilmesi(Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, 2007) Yazar, Abdullah; Karaaslan, SevimMitral yetmezlikli (MY) hastalarda, sol ventrikül fonksiyonlarının bozulduğunun erkensaptanmasında doku Doppler görüntülemelerinin (DDG) geleneksel yöntemlerden daha iyisonuç verdiği ileri sürülmektedir. Ancak çocukluk yaş grubundaki hastaların ameliyataverilme zamanını gösteren doku Doppler değerleri henüz belirlenmemiştir. Bu çalışmanınamacı, sol ventrikül fonksiyon bozukluğunun erken farkedilmesi açısından sağlıklı vedeğişik ağırlıklı MY'li çocuklardan geleneksel ve DDG yöntemleri ile elde edileceksonuçları karşılaştırmaktır.Hafif-orta derecede MY bulunan 20 hasta (grup 2), ağır derecede MY bulunan 10 hasta(grup 3) ve sağlıklı 30 çocuk (grup 1) çalışmaya dahil edilmiştir. Gruplar arasında yaş,vücut alanı, kan basıncı, kalp hızı gibi sonuçları etkileyecek parametreler açısından anlamlıbir farklılık mevcut değildir. Ekokardiyografik incelemeler Hawlett-Packard Sonos 5500ekokardiyografi cihazı ve 2.5 MHz'lik proplar kullanılarak yapılmıştır. MY'ninderecelendirilmesi jet alanının sol atriyuma oranı ve rügürjitan fraksiyonu kullanılarakyapılmıştır. Ejeksiyon fraksiyonu, fraksiyonel kısalma, pre-ejeksiyon periyodu (PEP),ejeksiyon zamanı (ET), PEP/ET oranı, aortik peak flow velosite, aortik peak velositeintegral, akselerasyon zamanı, aortik distansibilite, kardiyak indeks, interventrikülerseptumun kalınlaşma yüzdesi, sol ventrikül arka duvarının sistolik kalınlaşma yüzdesi, solventrikül sistol-sonu meridyonal duvar stresi, çembersel kısalmanın ortalama hızı, ortalamaakselerasyon açısından gruplar arasında anlamlı bir farklılık bulunmamıştır (P>0.05).Grup 3'te miyokard performans indeksleri (MPI) ve Tei indeksleri kontrol grubuna göreanlamlı bir artış göstermiş ve bulunan değerler normal değerlerden daha yüksekbulunmuştur. Geleneksel ve DDG ile bakılan izovolumik kontraksiyon ve relaksasyonzamanları, E ve A dalga velositeleri. E/A oranı, E-dekselerasyon zamanı, DDG ile bakılanEm /Am oranı, heriki yöntem ile değerlendilen E/Em oranı grup 3'te kontrol grubundananlamlı olarak farklı olduğu saptanmış ancak saptanan değerler literatürde bildirilennormal değerler arasında olduğu görülmüştür. Sonuçlarımız, tek bir DDG'nin LVfonksiyon bozukluğunun başlangıcını yeterince ortaya koyamadığı ve seri şekildeyapılacak takip incelemelerine gereksinim duyulduğu şeklindeki literatür bilgisinidesteklemiştir. Ameliyat sonrası gelişebilecek mortaliteyi öngörebilecek doku Dopplerdeğerlerinin tesbit edilebilmesi için çok sayıda vaka ile yapılacak çalışmalara ihtiyaçvardır.
