Akut Bronşiyolitte İzole Edilen Viral Patojenlerin ve Uygulanan Tedavi Yöntemlerinin Hastalığın Seyrine Etkisi
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Tarih
2017
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Giriş ve Amaç: Akut bronşiyolit süt çocukluğunda ve 2 yaşından küçük çocuklarda, genellikle viral etkenlere bağlı gelişen ve hastaneye yatışın majör sebeplerinden olan bir alt solunum yolu enfeksiyonudur. Çalışmamızın amacı akut bronşiolit nedeniyle hastanede yatan çocuklarda izole edilen laboratuvar bulguları ve uygulanan tedavi yöntemlerinin hastaların yatış sürelerine etkisini araştırmaktır.Yöntem ve Gereçler: Bu amaçla Konya Eğitim ve Araştırma Hastanesi Çocuk Kliniğinde Aralık 2013 - Mayıs 2014 tarihleri arasında bronşiyolit tanısıyla yatarak takip edilen 95 hastanın dosyaları retrospektif olarak incelendi.Bulgular: En fazla izole edilen viral patojenler respiratuvar sinsityal virüs (%21.8) ve rinovirüs idi (%21.8). Sadece rinovirüs üreyen grupla üreme olmayan grup arasında yatış süreleri açısından anlamlı bir fark bulunamazken, sadece RSV-A üreyen ve RSV-ARinovirüs birlikte üreyen grupta hastanede yatış süreleri anlamlı derecede uzun bulundu. İnhale bronkodilatatör, ipratropium bromid, hipertonik salin tedavisi uygulanan ve uygulanmayan hasta grupları arasında yatış süreleri açısından anlamlı fark saptanmazken, inhale streoid alan olguların yatış süresi almayanlara oranla daha uzun bulundu. İmmunglobulin E (Ig E) düzeyi yüksek ölçülen hastaların ortalama yatış süreleri, normal olanlara göre anlamlı olarak uzundu. Anne sütü alan ve almayan gruplar arasında ve sigara ile temas öyküsü olan ve olmayan gruplar arasında yatış süreleri açısından anlamlı fark saptanmadı.Tartışma ve Sonuç: Sonuç olarak, RSV ve rinovirüs hala akut bronşiyolitin majör sebepleridir. İnhale steroid tedavisi almak, yüksek Ig E düzeyi ve bronşiolit sebebinin RSV olması hastanede yatış süresini uzatmaktadır.
Introduction: Acute bronchiolitis, is predominantly a viral disease, part of the spectrum of lower respiratory tract diseases, and is a major cause of illness and hospitalization in infants and children younger than 2 years of age. The aim of the present study was to determine the effects of treatment protocols, other laboratory results, and isolated viral agents on the duration of hospitalization.Methods: Data of 95 children who were hospitalized with the diagnosis of bronchiolitis at the pediatrics clinic of KonyaTraining and Research Hospital between October 2013 and May 2014 were reviewed retrospectively.A Results: The most frequently seen agents were respiratory syncytial virus (RSV) and rhinovirus with an equal rate of 21.8%. When patients with no isolation were compared with patients with only rhinovirus isolated, no significant difference was found in hospitalization length. However, hospitalization duration was significantly longer in patients with RSV-A infection and RSV-A and rhinovirus, than in patients with no virus isolation. While hospitalization length was not affected by receiving inhaled bronchodilator treatment, ipratropium bromide or hypertonic saline, the duration was longer in patients receiving inhaled corticosteroid compared with patients who didn't receive inhaled corticosteroid. The mean hospitalization durationwas significantly longer in patients with higher immunoglobulin E (IG E) levels. Smoke exposure and receiving breast milk in the first 6 months of life didn't influencethe length of stay in hospital.Discussion and Conclusion: In conclusion, receiving inhaled corticosteroid, high Ig E level and bronchiolitis due to RSV infection prolonged hospital stay.
Introduction: Acute bronchiolitis, is predominantly a viral disease, part of the spectrum of lower respiratory tract diseases, and is a major cause of illness and hospitalization in infants and children younger than 2 years of age. The aim of the present study was to determine the effects of treatment protocols, other laboratory results, and isolated viral agents on the duration of hospitalization.Methods: Data of 95 children who were hospitalized with the diagnosis of bronchiolitis at the pediatrics clinic of KonyaTraining and Research Hospital between October 2013 and May 2014 were reviewed retrospectively.A Results: The most frequently seen agents were respiratory syncytial virus (RSV) and rhinovirus with an equal rate of 21.8%. When patients with no isolation were compared with patients with only rhinovirus isolated, no significant difference was found in hospitalization length. However, hospitalization duration was significantly longer in patients with RSV-A infection and RSV-A and rhinovirus, than in patients with no virus isolation. While hospitalization length was not affected by receiving inhaled bronchodilator treatment, ipratropium bromide or hypertonic saline, the duration was longer in patients receiving inhaled corticosteroid compared with patients who didn't receive inhaled corticosteroid. The mean hospitalization durationwas significantly longer in patients with higher immunoglobulin E (IG E) levels. Smoke exposure and receiving breast milk in the first 6 months of life didn't influencethe length of stay in hospital.Discussion and Conclusion: In conclusion, receiving inhaled corticosteroid, high Ig E level and bronchiolitis due to RSV infection prolonged hospital stay.
Açıklama
Anahtar Kelimeler
Akut bronşiyolit virüs, Çocuk, İnhale tedaviler, Yatış süresi, Acute bronchiolitis, Duration of hospitalization, İnhaler treatments, Virüs
Kaynak
Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
57
Sayı
2
Künye
Yazar, A. Akın, F., Arslan, Ş. (2017). Akut bronşiyolitte izole edilen viral patojenlerin ve uygulanan tedavi yöntemlerinin hastalığın seyrine etkisi. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, 57, 2, 63-67.
