A Rare Case: Improved Heart Failure with Anti-Complement Therapy in Complement-Dependent Hemolytic Uremic Syndrome

Basit Öğe Kaydı
dc.authoridHakan Özer: 0000-0001-9174-0351en_US
dc.authoridYasin Öztürk: 0000-0003-2634-2677en_US
dc.authoridKültigin Türkmen: 0000-0002-1667-7716en_US
dc.authoridHalil Zeki Tonbul: 0000-0003-0761-3697en_US
dc.authoridNedim Yılmaz Selçuk: 0000-0003-0836-7993en_US
dc.contributor.authorÖzer, Hakan
dc.contributor.authorÖztürk, Yasin
dc.contributor.authorTürkmen, Kültigin
dc.contributor.authorTonbul, Halil Zeki
dc.contributor.authorSelçuk, Nedim Yılmaz
dc.date.accessioned2023-05-11T09:20:17Z
dc.date.available2023-05-11T09:20:17Z
dc.date.issued2023en_US
dc.departmentNEÜ, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Anabilim Dalıen_US
dc.descriptionMakaleen_US
dc.descriptionWOS:000925209300014en_US
dc.description.abstractxtrarenal involvement occurs in approximately 20% of patients with complement-mediated hemolytic-uremic syndrome. The involvement is usually of the nervous system, and cardiac involvement occurs in 3%-10% of patients. Cardiac manifestations vary, including myocardial infarction, cardiomyopathy, and acute decompensated heart failure. Among these patients, thrombotic microangiopathy-related cardiac dysfunction is mainly due to the continuous activation of the complement system, which leads to endothelial damage and thrombosis in the coronary microvessels. We wanted to highlight the importance of cardiac evaluation at the time of diagnosis or during follow-up in thrombotic micro-angiopathy patients by presenting a case of heart failure with low ejection fraction in a 24-year-old young patient in whom we detected complement-mediated hemolytic-uremic syndrome, a secondary mutation of complement factor H receptor. It is still an unknown issue because of the rarity of cardiac involvement in complement-mediated hemolytic-uremic syndrome patients. Primary myocardial involvement is increasingly recognized as a possible concomitant feature of hemolytic-uremic syndrome. Failure to perform a detailed cardiac evaluation both at diagnosis and during follow-up in complement-mediated hemolytic-uremic syndrome patients can lead to fatal outcomes. Anti-complement therapy can also lead to good cardiac outcomes in these patients.en_US
dc.identifier.citationÖzer, H., Öztürk, Y., Türkmen, K., Tonbul, H. Z., Selçuk, N. Y. (2023). A rare case: Improved heart failure with anti-complement therapy in complement-dependent hemolytic uremic syndrome. Turkish Journal of Nephrology, 32, 1, 90-93.en_US
dc.identifier.doi10.5152/turkjnephrol.2023.2261342en_US
dc.identifier.endpage93en_US
dc.identifier.issn2667-4440en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage90en_US
dc.identifier.urihttp://dx.doi.org/10.5152/turkjnephrol.2023.2261342
dc.identifier.urihttps://hdl.handle.net/20.500.12452/9599
dc.identifier.volume32en_US
dc.identifier.wosWOS:000925209300014en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAVESen_US
dc.relation.ispartofTurkish Journal of Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute Kidney Injuryen_US
dc.subjectAnti-Complement Therapyen_US
dc.subjectComplement-Mediated Kemolytic-Uremic Syndromeen_US
dc.subjectHeart Failureen_US
dc.subjectThrombotic Microangiopathyen_US
dc.titleA Rare Case: Improved Heart Failure with Anti-Complement Therapy in Complement-Dependent Hemolytic Uremic Syndromeen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
A Rare Case Improved Heart Failure with Anti-Complement Therapy in Complement-Dependent Hemolytic Uremic Syndrome.pdf
Boyut:
1.19 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin (Full Text)
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu