Surgical treatment of phyllodes tumors of the breast: A single center experience
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Tarih
2013
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Dergi ISSN
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Memenin fillodes tümörü nadir görülen fibroepitelyal bir tümördür. Bu çalışmada memenin fillodes tümörü tanılı hastalarımızın klinikopatolojik bulgularını ve tedavi yaklaşımımızı sunmayı amaçladık. Yöntem ve Gereçler: Kliniğimizde 2003-2011 yılları arasında memenin fillodes tümörü nedeniyle tedavi gören 9 hastanın tıbbi kayıtları geriye dönük olarak incelendi. Bulgular: Hastaların ortanca yaşı 38 (20-70) yaş olarak saptanmıştır. Hastaların tümünün başvuru şikayeti memede ele gelen kitle idi. Hastalardan altısına kalın-iğne biyopsi, ikisine eksizyonel biyopsi, birine de ince iğne aspirasyon biyopsisi (İİAB) ile tanı konuldu. Ortalama tümör büyüklüğü 9.3 (4-20) cm olarak hesaplandı. İki hasta dışında tüm olgulara cerrahi sınır negatif olacak şekilde lokal eksizyon uygulandı ve adjuvan ek bir tedavi verilmedi. İki hastadan birine mastektomi, diğerine ise modifiye radikal mastektomi işlemi uygulandı. Hastalar ortalama 43 (5-95) ay takip edildi. Takip süresince hastalarda memede nüks saptanmadı. Sonuç: Bu olgularda preoperatif tanı cerrahi yaklaşımı belirlemek açısından önemlidir. Ayırıcı tanıda yapılan ultrasonografi ve mamografi gibi radyolojik tetkiklerde bu tümörleri fibroadenomdan ayırt etmek zordur. Doku biyopsisi ile tanıya gitmek mümkündür. Sonuç olarak, fillodes tümörler genellikle klinik ve patolojik olarak selim olduğundan tüm hastalarda sınır negatif olacak şekilde cerrahi yaklaşım düşünülmelidir.
Objective: Phyllodes tumor of the breast is a rare fibroepithelial tumor. In this study, our aim is to present the clinicopathological characteristics of our patients diagnosed with phyllodes tumor of the breast and our treatment ap- proach to the cases. Materials and Methods: The medical records of a total of 9 patients who had been treated at our clinic between 2003 and 2011 for phyllodes tumor were analyzed retrospectively. Results: The median age of the patients was 38 (20-70) years. The presenting complaint of all patients was a palpable mass in the breast. Six of the patients were diagnosed by tru-cut biopsy, two were diagnosed through excisional bi- opsy, and one was diagnosed through fine- needle aspiration biopsy (FNAB). Median tumor size was 9.3 (4-20) cm. Local excision was performed on all but two patients so as to have the surgical border negative and no adjuvant additional treatment was initiated. Mastectomy was performed for one of the two patients and modified radical mastectomy was performed for the other. The follow-up period of the patients was an average of 43 (5-95) months. No breast recurrences were seen during the follow-up period. Conclusion: Pre-operative diagnosis is important for these cases in order to determine the surgical approach. It is difficult to differentiate these tumors from fibroadenoma by ultrasonography and mammography. It is possible to diagnose patients through tissue biopsy. In conclusion, a surgical approach with negative margins for all patients should be taken into consideration since phyllodes tumors are generally benign both clinically and pathologically.
Objective: Phyllodes tumor of the breast is a rare fibroepithelial tumor. In this study, our aim is to present the clinicopathological characteristics of our patients diagnosed with phyllodes tumor of the breast and our treatment ap- proach to the cases. Materials and Methods: The medical records of a total of 9 patients who had been treated at our clinic between 2003 and 2011 for phyllodes tumor were analyzed retrospectively. Results: The median age of the patients was 38 (20-70) years. The presenting complaint of all patients was a palpable mass in the breast. Six of the patients were diagnosed by tru-cut biopsy, two were diagnosed through excisional bi- opsy, and one was diagnosed through fine- needle aspiration biopsy (FNAB). Median tumor size was 9.3 (4-20) cm. Local excision was performed on all but two patients so as to have the surgical border negative and no adjuvant additional treatment was initiated. Mastectomy was performed for one of the two patients and modified radical mastectomy was performed for the other. The follow-up period of the patients was an average of 43 (5-95) months. No breast recurrences were seen during the follow-up period. Conclusion: Pre-operative diagnosis is important for these cases in order to determine the surgical approach. It is difficult to differentiate these tumors from fibroadenoma by ultrasonography and mammography. It is possible to diagnose patients through tissue biopsy. In conclusion, a surgical approach with negative margins for all patients should be taken into consideration since phyllodes tumors are generally benign both clinically and pathologically.
Açıklama
Anahtar Kelimeler
Phyllodes tumor, Breast, Segmental mastectomy, Fillodes tümör, Meme, Segmental mastektomi
Kaynak
Meme Sağlığı Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
9
Sayı
2
