Konya ilindeki erişkin çölyak hastalarının epidemiyolojik, klinik ve laboratuvar bulgularının retrospektif olarak değerlendirilmesi
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Dosyalar
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada erişkin çölyak hastalarının (ÇH) epidemiyolojik ve klinik özelliklerini, diyetten fayda görüp görmediklerini ve laboratuvar parametrelerini değerlendirilmeyi amaçladık. Yöntem: Çalışmamızda 2011-2017 yılları arasında Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Hastanesi, İç Hastalıkları ABD, Gastroenteroloji Bilim Dalı Klinik ve Polikliniğinde çölyak tanısı ile takip edilen 18 yaş ve üzeri hastaların hastane otomasyon sistemi üzerinden retrospektif olarak değerlendirilmesi planlandı. Hastaların laboratuvar kayıtları incelendi ve anamnez kısmındaki bilgilerden tanı anındaki ve en son kontroldeki klinik özellikleri kayıt altına alındı. Bulgular:Çalışmaya toplam 155 çölyak hastası dahil edildi. Hastaların 119'u (%76.8) kadın, 36'sı (%23.2) erkekti ve yaş ortalamaları 37.1±13.7'ti. Ortalama çölyak tanı süresi 5.3±4.6 yıldı. Hastaların 54'ünün (%34.8) ailesinde ÇH tanısı mevcuttu. Hastaların BKİ ortalaması 24±4.4 kg/m2 olarak hesaplandı. Hastaların tanı anında ve son kontrolde en sık şikayeti dispepsiydi (%71.6 ve %20). Konstipasyon tanıda %25'inde mevcuttu. Diyete tam uyum oranı %70.3 olarak hesaplandı. Hipotiroidi en sık eşlik eden hastalıktı (%9.6). Toplam 22 (%14.1) farklı hastada en az bir otoimmün hastalık saptandı. Serolojik testlerin pozitiflik oranı %33.5 ile %63.9 arasındaydı. Hastaların %24'ünde demir eksikliği anemisi, %71'inde vitamin D eksikliği tespit edildi. Sonuç: Çölyak hastalığı hem tanı anında hem de takipte, klinik ve laboratuvar açısından oldukça heterojen bir tablo ile karşımıza çıkmaktadır. Özellikle, oldukça sık eşlik eden immün aracılı hastalıklar konusunda takip eden hekimlerin daha dikkatli olması gerekmektedir. Anahtar Kelimeler: Çölyak hastalığı, atipik çölyak hastalığı, komorbidite, otoimmünite
The Evaluation of Epidemiological, Clinical and Laboratory Findings of Adult Celiac Patients in Konya Province, Dr. Muhammed Muhiddin Er, Specialty Thesis, Konya, 2018 Aim:In this study, we aimed to evaluate the epidemiologic and clinical features and laboratory parameters of adult patients with celiac disease (CD), and whether they benefit from diet. Methods:In our study, it was planned to retrospectively evaluate the patients over the age of 18 years who were followed up with the diagnosis of CD in Necmettin Erbakan University, Meram Medical Faculty Hospital, Department of Internal Medicine and Gastroenterology between 2011 and 2017 via hospital automation system. The laboratory records of the patients were examined and the clinical features at the diagnosis and at the latest control were recorded from the information in the anamnesis section. Results:A total of 155 celiac patients were included in the study. 119 (76.8%) of the patients were female, 36 (23.2%) were male and mean age was 37.1±13.7 years. Mean duration of disease was 5.3±4.6 years. 54 (34.8%) of the patients had family history of CD. The mean BMI of the patients was 24±4.4 kg/m2. The most common complaint was dyspepsia at the time of diagnosis and at the last follow-up(71.6% and 20%, respectively). Constipation was present in 25% of the casesat the time of diagnosis. The rate of exact adherence to diet was 70.3%. Hypothyroidism was the most common accompanying disease (9.6%). At least one autoimmune disease was detected in 22(14.1%) patients. Serological test positivity ranged from 33.5% to 63.9%. 24% of the patients had iron deficiency anemia and 71% had vitamin D deficiency. Conclusion:Celiac disease is confronted with a very heterogeneous picture in terms of clinic and laboratory both at the time of diagnosis and in the follow-up. In particular, physicians should be more cautious about immuno-mediated diseases, which are quite often accompanied. Keywords:Celiac disease, atypical celiac disease, comorbidity, autoimmunity
The Evaluation of Epidemiological, Clinical and Laboratory Findings of Adult Celiac Patients in Konya Province, Dr. Muhammed Muhiddin Er, Specialty Thesis, Konya, 2018 Aim:In this study, we aimed to evaluate the epidemiologic and clinical features and laboratory parameters of adult patients with celiac disease (CD), and whether they benefit from diet. Methods:In our study, it was planned to retrospectively evaluate the patients over the age of 18 years who were followed up with the diagnosis of CD in Necmettin Erbakan University, Meram Medical Faculty Hospital, Department of Internal Medicine and Gastroenterology between 2011 and 2017 via hospital automation system. The laboratory records of the patients were examined and the clinical features at the diagnosis and at the latest control were recorded from the information in the anamnesis section. Results:A total of 155 celiac patients were included in the study. 119 (76.8%) of the patients were female, 36 (23.2%) were male and mean age was 37.1±13.7 years. Mean duration of disease was 5.3±4.6 years. 54 (34.8%) of the patients had family history of CD. The mean BMI of the patients was 24±4.4 kg/m2. The most common complaint was dyspepsia at the time of diagnosis and at the last follow-up(71.6% and 20%, respectively). Constipation was present in 25% of the casesat the time of diagnosis. The rate of exact adherence to diet was 70.3%. Hypothyroidism was the most common accompanying disease (9.6%). At least one autoimmune disease was detected in 22(14.1%) patients. Serological test positivity ranged from 33.5% to 63.9%. 24% of the patients had iron deficiency anemia and 71% had vitamin D deficiency. Conclusion:Celiac disease is confronted with a very heterogeneous picture in terms of clinic and laboratory both at the time of diagnosis and in the follow-up. In particular, physicians should be more cautious about immuno-mediated diseases, which are quite often accompanied. Keywords:Celiac disease, atypical celiac disease, comorbidity, autoimmunity
Açıklama
Anahtar Kelimeler
Epidemiyoloji, Epidemiology, Komorbidite, Comorbidity, Otoimmünite, Autoimmunity
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Er, M. M. (2018). Konya ilindeki erişkin çölyak hastalarının epidemiyolojik, klinik ve laboratuvar bulgularının retrospektif olarak değerlendirilmesi. (Yayınlanmamış tıpta uzmanlık tezi) Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Dahili Tıp Bilimleri İç Hastalıklar Anabilim Dalı, Konya.
