Silver nanoparticle doped graphene-based impedimetric biosensor towards sensitive detection of procalcitonin

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dc.authoridFaysal Selimoğlu: 0000-0001-7876-1035en_US
dc.contributor.authorSelimoğlu, Faysal
dc.contributor.authorGür, Bahri
dc.contributor.authorAyhan, Muhammed Emre
dc.contributor.authorGür, Fatma
dc.contributor.authorKalita, Golap
dc.contributor.authorTanemura, Masaki
dc.contributor.authorAlma, Mehmet Hakkı
dc.date.accessioned2023-06-01T09:49:11Z
dc.date.available2023-06-01T09:49:11Z
dc.date.issued2023en_US
dc.departmentNEÜ, Fen Fakültesi, Biyoteknolojien_US
dc.descriptionMakaleen_US
dc.descriptionWOS:000922183800001en_US
dc.description.abstractIn the early detection of sepsis, procalcitonin (PCT) appears to be a highly sensitive biomarker for severe inflammation and infection. A significant interaction between the electrode material to be used in the design of the biosensor and the material to be attached to the surface is of great importance. Here, we demonstrated a silver nanoparticle (AgNp) doped graphene-based sensitive PCT biosensor with low-cost, environmentally friendly materials. Cyclic voltammetry curves showing the reusability of the electrodes obtained were obtained and showed antibody-protein adhesion on the AgNp/SLG@ITO surface. The anodic and cathodic peak currents values after 20 cycles show that these values are suitable even after 20 measurements. Electrochemical impedance spectroscopy (EIS) studies confirmed the effects of PCT on binding events due to increasing con-centration at a constant PCT-antibody concentration. The limit of detection (LOD) value of the fabricated PCT/ Ab/AgNp/SLG@ITO impedimetric biosensor was determined as 0.55 ngmL-1. The low LOD value can be attributed to the uniform and large surface area of single-layer graphene (SLG) and noble AgNp. The LOD value based on the EIS studies has revealed that the PCT/Ab/AgNp/SLG@ITO impedimetric biosensor can be employed in real samples.en_US
dc.description.sponsorshipScientific Research Projects (BAP) Coordination Unit at Necmettin Erbakan University; Turkish Academy of Sciences (TUBA)en_US
dc.identifier.citationSelimoğlu, F., Gür, B., Ayhan, M. E., Gür, F., Kalita, G., Tanemura, M., Alma, M. H. (2023). Silver nanoparticle doped graphene-based impedimetric biosensor towards sensitive detection of procalcitonin. Materials Chemistry and Physics, 297, 1-10.en_US
dc.identifier.doi10.1016/j.matchemphys.2023.127339en_US
dc.identifier.endpage10en_US
dc.identifier.issn0254-0584en_US
dc.identifier.issn1879-3312en_US
dc.identifier.issue-en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.matchemphys.2023.127339
dc.identifier.urihttps://hdl.handle.net/20.500.12452/9755
dc.identifier.volume297en_US
dc.identifier.wosWOS:000922183800001en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofMaterials Chemistry and Physicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectCVD Grapheneen_US
dc.subjectImpedimetric Biosensoren_US
dc.subjectProcalcitoninen_US
dc.subjectSepsisen_US
dc.subjectEISen_US
dc.subjectThin Filmsen_US
dc.titleSilver nanoparticle doped graphene-based impedimetric biosensor towards sensitive detection of procalcitoninen_US
dc.typeArticleen_US

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