Evaluation of Appetite-Regulating Hormones in Young Children with Autism Spectrum Disorder

Küçük Resim Yok

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer/Plenum Publishers

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD.

Açıklama

Anahtar Kelimeler

Autism, Leptin, Ghrelin, Neuropeptide Y, Nesfatin-1, Early Childhood

Kaynak

Journal Of Autism And Developmental Disorders

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

51

Sayı

2

Künye