Evaluation of Appetite-Regulating Hormones in Young Children with Autism Spectrum Disorder

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dc.contributor.authorSadic, Cagla Celikkol
dc.contributor.authorBilgic, Ayhan
dc.contributor.authorKilinc, Ibrahim
dc.contributor.authorOflaz, Mehmet Burhan
dc.contributor.authorBaysal, Tamer
dc.date.accessioned2024-02-23T13:56:11Z
dc.date.available2024-02-23T13:56:11Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractThis study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD.en_US
dc.description.sponsorshipScientific Research Project Coordination Unit of Necmettin Erbakan University [181518012]en_US
dc.description.sponsorshipFunding for this study was provided by a grant from the Scientific Research Project Coordination Unit of Necmettin Erbakan University (Project No: 181518012).en_US
dc.identifier.doi10.1007/s10803-020-04579-0
dc.identifier.endpage643en_US
dc.identifier.issn0162-3257
dc.identifier.issn1573-3432
dc.identifier.issue2en_US
dc.identifier.pmid32583136en_US
dc.identifier.scopus2-s2.0-85087048990en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage632en_US
dc.identifier.urihttps://doi.org/10.1007/s10803-020-04579-0
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11119
dc.identifier.volume51en_US
dc.identifier.wosWOS:000543054000001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer/Plenum Publishersen_US
dc.relation.ispartofJournal Of Autism And Developmental Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAutismen_US
dc.subjectLeptinen_US
dc.subjectGhrelinen_US
dc.subjectNeuropeptide Yen_US
dc.subjectNesfatin-1en_US
dc.subjectEarly Childhooden_US
dc.titleEvaluation of Appetite-Regulating Hormones in Young Children with Autism Spectrum Disorderen_US
dc.typeArticleen_US

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