Liporotein-Associated Phospholipase-A2 Can Be A Diagnostic Marker İnthe Early Stage Diagnosis Of Acute Mesenteric İschemia

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dc.authorid0000-0001-8265-9615en_US
dc.authorid0000-0002-3308-5843en_US
dc.authorid0000-0002-9420-6514en_US
dc.contributor.authorAcar, Tarık
dc.contributor.authorKoçak, Sedat
dc.contributor.authorCander, Başar
dc.contributor.authorErgin, Mehmet
dc.contributor.authorDikmetaş, Cesareddin
dc.date.accessioned2020-01-18T21:02:52Z
dc.date.available2020-01-18T21:02:52Z
dc.date.issued2016
dc.departmentNEÜ, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Acil Tıp Anabilim Dalıen_US
dc.description.abstractBackground/aim: The purpose of this experimental study was to investigate the role of lipoprotein-associated phospholipase-A2 (LpPLA2 ) in the diagnosis of acute mesenteric ischemia (AMI) in the early stage. Materials and methods: Twenty-seven New Zealand rabbits were randomly divided into 3 groups in this study. Blood specimens were obtained from the groups at hours 0, 1, 3, and 6. Using the blood samples drawn from all groups, Lp-PLA2 and C-reactive protein (CRP) parameters were investigated. Results: There was a significant rise in the levels of both Lp-PLA2 and CRP starting at hour 1 (P > 0.05) (hour 1; Lp-PLA2 , P 0.003) in the ischemia group. In the sham group, the levels of Lp-PLA2 and CRP started to rise at hour 3 (P > 0.05) (hour 3; Lp-PLA2 , P 0.011). At hour 6 of ischemia, the area under the ROC curve was 100%, and the cut-off value of 63.91 ng/mL revealed a sensitivity of 88% and a specificity of 100% for Lp-PLA2 . Conclusion: These findings showed the role of serum Lp-PLA2 and CRP levels in the early diagnosis of AMI. Thus, further studies are needed to describe the role of Lp-PLA2 in the early diagnosis of AMI.en_US
dc.identifier.citationAcar, T., Koçak, S., Cander, B., Ergin, M., & Dikmetaş, C. (2016). Liporotein-Associated Phospholipase-A2 Can Be A Diagnostic Marker İnthe Early Stage Diagnosis Of Acute Mesenteric İschemia. Turkish Journal of Medical Sciences, 46, 1, 120-5.en_US
dc.identifier.endpage125en_US
dc.identifier.issn1300-0144en_US
dc.identifier.issn1303-6165en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage120en_US
dc.identifier.urihttp://app.trdizin.gov.tr/publication/paper/detail/TWpRM056QXpNdz09
dc.identifier.urihttps://hdl.handle.net/20.500.12452/1327
dc.identifier.volume46en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerrahien_US
dc.subjectAcute Mesenteric İschemiaen_US
dc.subjectLipoprotein-Associated Phospholipase-A2en_US
dc.subjectC-Reactive Proteinen_US
dc.subjectExperimental Studyen_US
dc.titleLiporotein-Associated Phospholipase-A2 Can Be A Diagnostic Marker İnthe Early Stage Diagnosis Of Acute Mesenteric İschemiaen_US
dc.typeArticleen_US

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