Rib fractures: Could we accelerate the healing?

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dc.contributor.authorCalik, Mustafa
dc.contributor.authorCalik, Saniye Goknil
dc.contributor.authorDagli, Mustafa
dc.contributor.authorAvunduk, Mustafa Cihat
dc.date.accessioned2024-02-23T14:40:45Z
dc.date.available2024-02-23T14:40:45Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractAim: We thought about How fractures are improving more rapidly. For this purpose, we made an experimental model to investigate the effect of zinc supplementation on the development of new bone in young rabbits. Material and Method: Six weeks of age, male New Zealand white rabbits were evaluated in four groups, each including five subjects. To simulate the RFs, subperichondrial costal cartilage resections beginning from the third costal cartilage were carried out in the right hemithorax according to groups. Rabbits in Group 1 and 2 underwent partial resection of the two ribs; rabbits in Group 3 and 4 underwent total resection of those. Zinc was administered by intraperitoneal injection of 6 mg/kg/ day for four weeks after the surgery for group 2 and 4. The animals were followed-up at the twenty-fourth week of their life. Results: We analyzed histologic changes in the bone. There were statistically significant differences for osteoblasts and osteoclasts among all subgroups. Histologic consolidation was significantly increased by zinc supplementation. According to the literature, in our study, while zinc stimulates osteoblastic bone formation, suppresses osteoclastic bone resorption. Discussion: Although the proper treatment of rib fracture (RF), long-term disability and persistent chest wall pain frequently develop and may take several months to recover, leads to the high hospital, medicine, labor, and social burden. Our findings indicate that zinc supplementation accelerates the consolidation of ribs. Zinc can be used to increase the bone maturation such as the site of new bone formation in RF.en_US
dc.description.sponsorshipSchool of Medicine Animal Careen_US
dc.description.sponsorshipThis study was approved and funded by the School of Medicine Animal Care and Investi-gational Committee in our institution.en_US
dc.identifier.doi10.4328/ACAM.6156
dc.identifier.endpage90en_US
dc.identifier.issn2667-663X
dc.identifier.issue2en_US
dc.identifier.startpage86en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.6156
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16561
dc.identifier.volume11en_US
dc.identifier.wosWOS:000572683300001en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals Of Clinical And Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectZincen_US
dc.subjectSupplementationen_US
dc.subjectRib Fractureen_US
dc.subjectRabbitsen_US
dc.titleRib fractures: Could we accelerate the healing?en_US
dc.typeArticleen_US

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