A Special Chromosome Imbalance Jumping translocation of 1q in Burkitt Lymphoma

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dc.contributor.authorTuran, Betul
dc.contributor.authorGoktas, Emine
dc.contributor.authorZamani, Ayse Gul
dc.contributor.authorTokgoz, Huseyin
dc.contributor.authorYildirim, Mahmut Selman
dc.date.accessioned2024-02-23T14:31:26Z
dc.date.available2024-02-23T14:31:26Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractChromosome 1q gain that confers clonal expansion advantage to tumor cells has been reported in many solid tissue and hematological cancers, in many different forms; sometimes as a derivative chromosome, as isochromosome, or less frequently, due to an imbalance created by a jumping translocation. Although it is known that chromosome 1q gain provide the advantage of clonal expansion to the tumor cells and is relatively common in Burkitt lymphoma/leukemia, its detection in the form of jumping translocation is extraordinarily rare and results of JT containing 1q are controversial. Bone marrow cytogenetic examination performed on a case diagnosed with stage 4 Burkitt lymphoma/leukemia resulted in 46,XY,dup(1)(q21q42),t(8;14)(q24;q32)[5]/46,XY,der(6)t(1;6)(q21;q27),t(8;14)(q 24;q32)[4]/46,XY,t(8;14)(q24;q32), der(11)t(1;11)(q21;q23 )[2]/46,XY[3]. We present the clinical features of the case that was found to have 1q gain in the jumping translocation form to contribute to the literature.en_US
dc.identifier.doi10.12996/gmj.2022.68
dc.identifier.endpage293en_US
dc.identifier.issn2147-2092
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85133690631en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage291en_US
dc.identifier.urihttps://doi.org/10.12996/gmj.2022.68
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15186
dc.identifier.volume33en_US
dc.identifier.wosWOS:000823151400020en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGazi Univ, Fac Meden_US
dc.relation.ispartofGazi Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBurkitt's Leukemiaen_US
dc.subjectBurkitt's Lymphomaen_US
dc.subjectBone Marrowen_US
dc.subjectCytogenetic Abnormalitiesen_US
dc.subjectTranslocationen_US
dc.subjectChromosomalen_US
dc.titleA Special Chromosome Imbalance Jumping translocation of 1q in Burkitt Lymphomaen_US
dc.typeArticleen_US

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