Fibromiyalji sendromlu kadın hastalarda sarkopeni değerlendirmesi
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Tarih
2024
Yazarlar
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Cilt Başlığı
Yayıncı
Necmettin Erbakan Üniversitesi, Tıp Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Fibromiyalji Sendromu (FMS) tanılı kadın hastalarda total ve bölgesel kas kütle ölçümleri ile tanı algoritmaları doğrultusunda sarkopeninin değerlendirilmesi amaçlandı.
Yöntem: Çalışmaya Amerikan Romatoloji Derneği (ACR) 2016 kriterlerine göre FMS tanısı alan 60 kadın hasta ve 30 sağlıklı kadın dahil edildi. Sosyodemografik özellikler ve antropometrik ölçümler not edilerek Yaygın Ağrı Skalası (YAS), Semptom Şiddet Skalası (SŞS), Görsel Analog Skala (GAS), Yorgunluk Şiddet Ölçeği (YŞÖ), Beck Depresyon Ölçeği (BDÖ), Uluslararası Fiziksel Aktivite Anketi (UFAA), Fibromiyalji Etki Anketi (FEA) ile katılımcılar değerlendirildi. El kavrama kuvveti değerlendirmesi, sandalyeden kalkma testi, biyoelektrik impedans analizi, ultrasonografi ile ön uyluk kas kalınlığının ölçümü, yürüme hızı değerlendirmesi, zamanlı kalk ve yürü testi yapılarak sarkopeni parametreleri kaydedildi. Tüm katılımcılar European Working Group on Sarcopenia in Older People 2 (EWGSOP2) ve International Society of Physical and Rehabilitation Medicine Special Interest Group on Sarcopenia (ISarcoPRM) tanı algoritmaları doğrultusunda sarkopeni açısından değerlendirildi.
Bulgular: Hasta grubunun el kavrama kuvveti ve yürüme hızı değerleri kontrol grubundan düşük, sandalyeden kalkma testi değeri kontrol grubundan yüksek saptandı; gruplar arasında istatistiksel olarak anlamlı farklılık vardı (p<0,01). ISarcoPRM tanı algoritmasına göre hasta grubunun %35’inin (n=21) muhtemel sarkopeni olduğu belirlendi. Muhtemel sarkopeni olanların %90,48’i (n=19) dinapeni olarak tanımlanırken, 2 kişi ise sarkopeni olarak tanımlandı. Hasta grubu ve kontrol grubu arasında ön uyluk kas kalınlığı, sonografik uyluk ayarlama oranı (STAR), iskelet kas kütlesi indeksi (SMI) açısından istatistiksel olarak anlamlı bir farklılık saptanmadı (p=0,897, p=0,829, p=0,706).
Sonuç: Fibromiyaljili kadınlarda ön planda kas fonksiyonunda azalma söz konusudur. Erken dönemde sarkopeni riskinin olmadığını göstermek için ileri çalışmalara ihtiyaç vardır.
Objective: The aim of this study is to evaluate sarcopenia in female patients with Fibromyalgia Syndrome (FMS) according to diagnostic algorithms with total and regional muscle mass measurements. Method: The study included 60 female patients diagnosed with FMS according to the American College of Rheumatology 2016 criteria and 30 healthy women. Sociodemographic characteristics and anthropometric measurements were noted and participants were evaluated using the Widespread Pain Index, Symptom Severity Scale, Visual Analog Scale, Fatigue Severity Scale, Beck Depression Inventory, International Physical Activity Questionnaire, Fibromyalgia Impact Questionnaire. Hand grip strength assessment, chair stand test, bioelectrical impedance analysis, measurement of anterior thigh muscle thickness by ultrasonography, gait speed assessment, timed up and go test were performed and sarcopenia parameters were recorded. All participants were evaluated for sarcopenia according to the EWGSOP2 and ISarcoPRM diagnostic algorithms. Results: Hand grip strength and walking speed values of the patient group were lower than those of the control group, and the chair stand test value was higher than that of the control group. There was a statistically significant difference between the groups (p<0.01). According to the ISarcoPRM diagnostic algorithm, 35% of the patient group (n=21) were found to have probable sarcopenia. While 90.48% (n=19) of those with probable sarcopenia were defined as dynapenia, 2 people were defined as sarcopenia. No statistically significant difference was found between the patient group and the control group in terms of anterior thigh muscle thickness, sonographic thigh adjustment ratio (STAR), skeletal muscle mass index (SMI) (p=0.897, p=0.829, p=0.706). Conclusion: Women with fibromyalgia have a decrease in muscle function in the foreground. Further studies are needed to show that there is no risk of sarcopenia in the early period.
Objective: The aim of this study is to evaluate sarcopenia in female patients with Fibromyalgia Syndrome (FMS) according to diagnostic algorithms with total and regional muscle mass measurements. Method: The study included 60 female patients diagnosed with FMS according to the American College of Rheumatology 2016 criteria and 30 healthy women. Sociodemographic characteristics and anthropometric measurements were noted and participants were evaluated using the Widespread Pain Index, Symptom Severity Scale, Visual Analog Scale, Fatigue Severity Scale, Beck Depression Inventory, International Physical Activity Questionnaire, Fibromyalgia Impact Questionnaire. Hand grip strength assessment, chair stand test, bioelectrical impedance analysis, measurement of anterior thigh muscle thickness by ultrasonography, gait speed assessment, timed up and go test were performed and sarcopenia parameters were recorded. All participants were evaluated for sarcopenia according to the EWGSOP2 and ISarcoPRM diagnostic algorithms. Results: Hand grip strength and walking speed values of the patient group were lower than those of the control group, and the chair stand test value was higher than that of the control group. There was a statistically significant difference between the groups (p<0.01). According to the ISarcoPRM diagnostic algorithm, 35% of the patient group (n=21) were found to have probable sarcopenia. While 90.48% (n=19) of those with probable sarcopenia were defined as dynapenia, 2 people were defined as sarcopenia. No statistically significant difference was found between the patient group and the control group in terms of anterior thigh muscle thickness, sonographic thigh adjustment ratio (STAR), skeletal muscle mass index (SMI) (p=0.897, p=0.829, p=0.706). Conclusion: Women with fibromyalgia have a decrease in muscle function in the foreground. Further studies are needed to show that there is no risk of sarcopenia in the early period.
Açıklama
Anahtar Kelimeler
Fibromiyalji, Fibromyalgia, kas, muscle, sarkopeni, sarcopenia, ultrasonografi, ultrasonography
Kaynak
WoS Q Değeri
Scopus Q Değeri
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Sayı
Künye
Karvanlı, S. (2024). Fibromiyalji sendromlu kadın hastalarda sarkopeni değerlendirmesi. (Yayınlanmamış tıpta uzmanlık tezi) Necmettin Erbakan Üniversitesi, Tıp Fakültesi Dahili Tıp Bilimleri Bölümü Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Konya.
